[HTML][HTML] A review and database of snake venom proteomes

T Tasoulis, GK Isbister - Toxins, 2017 - mdpi.com
Advances in the last decade combining transcriptomics with established proteomics
methods have made possible rapid identification and quantification of protein families in …

Snake venom peptides: Tools of biodiscovery

A Munawar, SA Ali, A Akrem, C Betzel - Toxins, 2018 - mdpi.com
Nature endowed snakes with a lethal secretion known as venom, which has been fine-tuned
over millions of years of evolution. Snakes utilize venom to subdue their prey and to survive …

[PDF][PDF] Antivenomics and its role in enhancing cobra envenomation treatments: A review of current practices and future prospects

I Karunarathna, K De Alvis, P Gunasena… - 2024 - researchgate.net
The King Cobra (Ophiophagus hannah) holds cultural significance and is one of the most
medically important venomous snakes worldwide. Envenomation by King Cobras often …

[PDF][PDF] Innovative approaches to neutralizing cobra venom: Advances in antivenomics and recombinant antivenoms

I Karunarathna, K De Alvis, P Gunasena… - 2024 - researchgate.net
The King Cobra (Ophiophagus hannah) holds cultural significance and is one of the most
medically important venomous snakes worldwide. Envenomation by King Cobras often …

Convergent evolution of pain-inducing defensive venom components in spitting cobras

TD Kazandjian, D Petras, SD Robinson, J van Thiel… - Science, 2021 - science.org
Convergent evolution provides insights into the selective drivers underlying evolutionary
change. Snake venoms, with a direct genetic basis and clearly defined functional …

Snake venomics: fundamentals, recent updates, and a look to the next decade

CH Tan - Toxins, 2022 - mdpi.com
Venomic research, powered by techniques adapted from proteomics, transcriptomics, and
genomics, seeks to unravel the diversity and complexity of venom through which knowledge …

Cytotoxicity of Snake Venoms and Cytotoxins From Two Southeast Asian Cobras (Naja sumatrana, Naja kaouthia): Exploration of Anticancer Potential, Selectivity …

HP Chong, KY Tan, CH Tan - Frontiers in Molecular Biosciences, 2020 - frontiersin.org
Venoms of cobras (Naja spp.) contain high abundances of cytotoxins, which contribute to
tissue necrosis in cobra envenomation. The tissue-necrotizing activity of cobra cytotoxins …

A pan-specific antiserum produced by a novel immunization strategy shows a high spectrum of neutralization against neurotoxic snake venoms

K Ratanabanangkoon, KY Tan, K Pruksaphon… - Scientific Reports, 2020 - nature.com
Snakebite envenomation is a neglected tropical disease of high mortality and morbidity
largely due to insufficient supply of effective and affordable antivenoms. Snake antivenoms …

Proteomics, functional characterization and antivenom neutralization of the venom of Pakistani Russell's viper (Daboia russelii) from the wild

T Faisal, KY Tan, SM Sim, N Quraishi, NH Tan… - Journal of …, 2018 - Elsevier
The venom proteome of wild Pakistani Russell's viper (Daboia russelii) was investigated
through nano-ESI-LCMS/MS of the reverse-phase HPLC fractions. A total of 54 venom …

[HTML][HTML] Antibody cross-reactivity in antivenom research

L Ledsgaard, TP Jenkins, K Davidsen, KE Krause… - Toxins, 2018 - mdpi.com
Antivenom cross-reactivity has been investigated for decades to determine which
antivenoms can be used to treat snakebite envenomings from different snake species …