Building a functional salivary gland for cell-based therapy: More than secretory epithelial acini

CML Barrows, D Wu, MC Farach-Carson… - … Engineering Part A, 2020 - liebertpub.com
A few treatment options exist for patients experiencing xerostomia due to hyposalivation that
occurs as a result of disease or injury to the gland. An opportunity for a permanent solution …

Three‐dimensional neuron–astrocyte construction on matrigel enhances establishment of functional voltage‐gated sodium channels

S Karahuseyinoglu, E Sekerdag… - Journal of …, 2021 - Wiley Online Library
This study aimed to investigate and compare cell growth manners and functional differences
of primary cortical neurons cultured on either poly‐d‐lysine (PDL) and or Matrigel, to …

Major depression-related factor NEGR1 controls salivary secretion in mouse submandibular glands

J Lee, S Kim, B Lee, YB Kim, KH Kim, G Chung, SJ Lee… - Iscience, 2023 - cell.com
Salivary gland cells, which secrete water in response to neuronal stimulation, are closely
connected to other neurons. Transcriptomic studies show that salivary glands also express …

[HTML][HTML] Strategies for develo** functional secretory epithelia from porcine salivary gland explant outgrowth culture models

G Urkasemsin, P Castillo, S Rungarunlert… - Biomolecules, 2019 - mdpi.com
Research efforts have been made to develop human salivary gland (SG) secretory epithelia
for transplantation in patients with SG hypofunction and dry mouth (xerostomia). However …

Exploring fibroblast heterogeneity in the formation of TLS in the context of primary Sjögrens syndrome

S Asam - 2022 - etheses.bham.ac.uk
The immune system is vital in the protection and maintenance of the body in a healthy state
against extracellular pathogens, tissue injury and self-antigens (autoimmunity). Tertiary …

[KNIHA][B] Salivary Gland Radioprotective Drug Screening

L Piraino - 2022 - search.proquest.com
Radiation-induced salivary gland dysfunction (xerostomia) is a common complication for
head and neck cancer patients. Damage to the salivary glands leads to hyposalivation …

The regulation of calcium signal and ion channels in salivary gland

이지수 - 2021 - s-space.snu.ac.kr
The regulation of saliva secretion is essential for daily life and the main function of the
exocrine salivary gland. The salivation is well known to be regulated via muscarinic receptor …