Nuclear blebs are associated with destabilized chromatin-packing domains

EM Pujadas Liwag, N Acosta… - Journal of Cell …, 2025 - journals.biologists.com
Disrupted nuclear shape is associated with multiple pathological processes including
premature aging disorders, cancer-relevant chromosomal rearrangements and DNA …

[HTML][HTML] Nuclear Structure, Size Regulation, and Role in Cell Migration

Y Li, S Ge, J Liu, D Sun, Y **, P Chen - Cells, 2024 - mdpi.com
The nucleus serves as a pivotal regulatory and control hub in the cell, governing numerous
aspects of cellular functions, including DNA replication, transcription, and RNA processing …

Decreased DNA density is a better indicator of a nuclear bleb than lamin B loss

S Bunner, K Prince, EM Pujadas Liwag… - Journal of Cell …, 2025 - journals.biologists.com
Nuclear blebs are herniations of the nucleus that occur in diseased nuclei and cause
nuclear rupture leading to cellular dysfunction. Chromatin and lamins are two of the major …