Cancer‑associated fibroblast regulation of tumor neo‑angiogenesis as a therapeutic target in cancer
FT Wang, WEI Sun, JT Zhang… - Oncology letters, 2019 - spandidos-publications.com
Adequate blood supply is essential for tumor survival, growth and metastasis. The tumor
microenvironment (TME) is dynamic and complex, comprising cancer cells, cancer …
microenvironment (TME) is dynamic and complex, comprising cancer cells, cancer …
Regulatory mechanisms and therapeutic targeting of vasculogenic mimicry in hepatocellular carcinoma
N Zheng, S Zhang, W Wu, N Zhang, J Wang - Pharmacological Research, 2021 - Elsevier
Hepatocellular carcinoma (HCC) is a typical hyper-vascular solid tumor; aberrantly rich in
tumor vascular network contributes to its malignancy. Conventional anti-angiogenic …
tumor vascular network contributes to its malignancy. Conventional anti-angiogenic …
Research progress on arsenic, arsenic-containing medicinal materials, and arsenic-containing preparations: clinical application, pharmacological effects, and toxicity
Y Yang, Y Li, R Li, Z Wang - Frontiers in pharmacology, 2024 - frontiersin.org
Introduction: The toxicity of arsenic is widely recognized globally, mainly harming human
health by polluting water, soil, and food. However, its formulations can also be used for the …
health by polluting water, soil, and food. However, its formulations can also be used for the …
Arsenic trioxide induces apoptosis and the formation of reactive oxygen species in rat glioma cells
Y Sun, C Wang, L Wang, Z Dai, K Yang - Cellular & Molecular Biology …, 2018 - Springer
Abstract Background Arsenic trioxide (As 2 O 3) has a dramatic therapeutic effect on acute
promyelocytic leukemia (APL) patients. It can also cause apoptosis in various tumor cells …
promyelocytic leukemia (APL) patients. It can also cause apoptosis in various tumor cells …
Nanocarrier-based delivery of arsenic trioxide for hepatocellular carcinoma therapy
J Sun, M Cheng, T Ye, B Li, Y Wei, H Zheng… - …, 2022 - Taylor & Francis
Hepatocellular carcinoma (HCC) poses a severe threat to human health and economic
development. Despite many attempts at HCC treatment, most are inevitably affected by the …
development. Despite many attempts at HCC treatment, most are inevitably affected by the …
Overcoming the therapeutic resistance of hepatomas by targeting the tumor microenvironment
J Zhang, H Han, L Wang, W Wang, M Yang… - Frontiers in …, 2022 - frontiersin.org
Hepatocellular carcinoma (HCC) accounts for the majority of primary liver cancers and is the
third leading cause of cancer-related mortality worldwide. Multifactorial drug resistance is …
third leading cause of cancer-related mortality worldwide. Multifactorial drug resistance is …
Arsenic Trioxide Decreases Lymphangiogenesis by Inducing Apoptotic Pathways and Inhibition of Important Endothelial Cell Receptors
I Hrgovic, E Zöller, M Doll, T Hailemariam-Jahn… - Current Issues in …, 2023 - mdpi.com
Tumor-induced lymphangiogenesis is strongly associated with the formation of tumor
metastasis. Therefore, the regulation of lymphangiogenesis offers a promising target in …
metastasis. Therefore, the regulation of lymphangiogenesis offers a promising target in …
Arsenic trioxide-loaded CalliSpheres: In vitro study of drug release and antitumor activity, and in vivo study of pharmacokinetics, treatment efficacy and safety in liver …
X Duan, G Zhao, X Han, J Ren, H Li… - Oncology …, 2021 - spandidos-publications.com
The aim of the present study was to investigate the arsenic trioxide (ATO) loading/releasing
efficiency of CalliSphere beads (CBs), as well as the in vitro anticancer activity, in vivo …
efficiency of CalliSphere beads (CBs), as well as the in vitro anticancer activity, in vivo …
The inhibitory effect on tumor cells proliferation induced by arsenic through dnmts and its downstream molecules: A systematic review and meta-analysis
J Zhang, S Li, M Ma, S Li - Current Pharmaceutical Design, 2022 - ingentaconnect.com
Background: We aimed to systematically evaluate the regulatory effect of arsenic on DNMTs
and its downstream molecules in tumor cells and to provide a theoretical framework …
and its downstream molecules in tumor cells and to provide a theoretical framework …
Transcatheter arterial chemoembolization using CalliSpheres beads loaded with arsenic trioxide for unresectable large or huge hepatocellular carcinoma: a …
X Duan, H Li, P Chen, T Sun, D Kuang, H Lu, B Qiao… - European …, 2024 - Springer
Objectives To determine the safety and efficacy of transcatheter arterial chemoembolization
with CalliSpheres® beads loaded with arsenic trioxide (CBATO-TACE) in the first-line …
with CalliSpheres® beads loaded with arsenic trioxide (CBATO-TACE) in the first-line …