The novel virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused
a pandemic of coronavirus disease 2019 (COVID-19). Across the globe, a subset of patients …

Mitochondria are the energy center of the cell. They are found in the cell cytoplasm as
dynamic networks where they adapt energy production based on the cell's needs. They are …

Phosphoglycerate dehydrogenase (PHGDH) has emerged as a crucial factor in
macromolecule synthesis, neutralizing oxidative stress, and regulating methylation reactions …

Serine/glycine biosynthesis and one-carbon metabolism are crucial in sustaining cancer cell
survival and rapid proliferation, and of high clinical relevance. Excessive activation of …

The SLC25 carrier family consists of 53 transporters that shuttle nutrients and co-factors
across mitochondrial membranes. The family is highly redundant and their transport …

One-carbon metabolism is a central metabolic pathway critical for the biosynthesis of several
amino acids, methyl group donors, and nucleotides. The pathway mostly relies on the …

Defences to pathogens such as SarCoV2 in mammals involves interactions between
immune functions and metabolic pathways to eradicate infection while preventing …

After infection of B cells, Epstein-Barr virus (EBV) engages host pathways that mediate cell
proliferation and transformation, contributing to the propensity of the virus to drive immune …

Background Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a chronic
disease considered to be triggered by viral infections in a majority of cases. Symptoms …

SARS-CoV-2 has been confirmed in over 450 million confirmed cases since 2019. Although
several vaccines have been certified by the WHO and people are being vaccinated on a …