Zinc finger E-box binding homeobox 1 (ZEB1) is a transcription factor that promotes tumor
invasion and metastasis by inducing epithelial-mesenchymal transition (EMT) in carcinoma …

MicroRNAs (miRNAs) are small non-coding RNAs regulating post-transcriptional gene
expression. They play important roles in many biological processes under physiological or …

De novo and acquired resistance, which are largely attributed to genetic alterations, are
barriers to effective anti-epidermal-growth-factor-receptor (EGFR) therapy. To generate …

Background Human mesenchymal stem cells (MSCs) have been shown to be involved in
the formation and modulation of tumor stroma and in interacting with tumor cells, partly …

Mutant KRAS colorectal cancer (CRC) cells release protein-laden exosomes that can alter
the tumor microenvironment. To test whether exosomal RNAs also contribute to changes in …

Stem cell‐based therapies exhibit profound therapeutic potential for treating various human
diseases, including cancer. Among the cell types that can be used for this purpose …

Metastasis is the main cause of cancer mortality for many types of cancer; however,
difficulties remain in effectively preventing metastasis. It has been recently and widely …

TWIST1 is a basic helix-loop-helix (bHLH) transcription factor which plays essential and
pivotal roles in multiple stages of embryonic development, and significantly contributes to …

Colorectal cancer (CRC) is the third most common cancer and leading cause of cancer
related deaths worldwide. Despite recent advancements in surgical and molecular targeted …

Triple-negative breast cancer (TNBC) exhibits poor prognosis, with high metastasis and low
survival. Long non-coding RNAs (lncRNAs) play critical roles in tumor progression. Here, we …