Long noncoding RNAs in viral infections

P Fortes, KV Morris - Virus research, 2016 - Elsevier
Viral infections induce strong modifications in the cell transcriptome. Among the RNAs
whose expression is altered by infection are long noncoding RNAs (lncRNAs). LncRNAs are …

lncRNAs regulate the innate immune response to viral infection

J Ouyang, J Hu, JL Chen - Wiley Interdisciplinary Reviews …, 2016 - Wiley Online Library
Long noncoding RNAs (lncRNAs) are extensively expressed in mammalian cells and play a
crucial role as RNA regulators in various cellular processes. Increasing data reveal that they …

An interferon-independent lncRNA promotes viral replication by modulating cellular metabolism

P Wang, J Xu, Y Wang, X Cao - Science, 2017 - science.org
Viruses regulate host metabolic networks to improve their survival. The molecules that are
responsive to viral infection and regulate such metabolic changes are hardly known, but are …

Long noncoding RNA EGOT negatively affects the antiviral response and favors HCV replication

E Carnero, M Barriocanal, C Prior, J Pablo Unfried… - EMBO …, 2016 - embopress.org
The role of long noncoding RNA s (lnc RNA s) in viral infection is poorly studied. We have
identified hepatitis C virus (HCV)‐S timulated lnc R NA s (CSR s) by transcriptome analysis …

Long noncoding RNA Lnc-MxA inhibits beta interferon transcription by forming RNA-DNA triplexes at its promoter

X Li, G Guo, M Lu, W Chai, Y Li, X Tong, J Li… - Journal of …, 2019 - Am Soc Microbiol
Previously, we identified a set of long noncoding RNAs (lncRNAs) that were differentially
expressed in influenza A virus (IAV)-infected cells. In this study, we focused on lnc-MxA …

Long non-coding RNAs: regulators of viral infection and the interferon antiviral response

L Qiu, T Wang, Q Tang, G Li, P Wu, K Chen - Frontiers in microbiology, 2018 - frontiersin.org
Interferons (IFNs) are a family of cytokines providing a robust first line of host innate defense
against pathogenic infection, and have now been part of the standard treatment for viral …

Long non-coding RNA BST2/BISPR is induced by IFN and regulates the expression of the antiviral factor tetherin

M Barriocanal, E Carnero, V Segura… - Frontiers in …, 2015 - frontiersin.org
Many long non-coding RNAs (lncRNAs) are expressed in cells but only a few have been
well characterized. In these cases, lncRNAs have been shown to be key regulators of …

Long noncoding RNA# 32 contributes to antiviral responses by controlling interferon-stimulated gene expression

H Nishitsuji, S U**o, S Yoshio… - Proceedings of the …, 2016 - National Acad Sciences
Despite the breadth of knowledge that exists regarding the function of long noncoding RNAs
(lncRNAs) in biological phenomena, the role of lncRNAs in host antiviral responses is poorly …

LncRNAs in HCV infection and HCV-related liver disease

JP Unfried, P Fortes - International Journal of Molecular Sciences, 2020 - mdpi.com
Long non-coding RNAs (lncRNAs) are transcripts with poor coding capacity that may interact
with proteins, DNA, or other RNAs to perform structural and regulatory functions. The …

LncRNAs in the type I interferon antiviral response

B Suarez, L Prats-Mari, JP Unfried, P Fortes - International Journal of …, 2020 - mdpi.com
The proper functioning of the immune system requires a robust control over a delicate
equilibrium between an ineffective response and immune overactivation. Poor responses to …