Bridging biological and artificial neural networks with emerging neuromorphic devices: fundamentals, progress, and challenges
As the research on artificial intelligence booms, there is broad interest in brain‐inspired
computing using novel neuromorphic devices. The potential of various emerging materials …
computing using novel neuromorphic devices. The potential of various emerging materials …
Computational models link cellular mechanisms of neuromodulation to large-scale neural dynamics
Decades of neurobiological research have disclosed the diverse manners in which the
response properties of neurons are dynamically modulated to support adaptive cognitive …
response properties of neurons are dynamically modulated to support adaptive cognitive …
Neural circuit basis of placebo pain relief
Placebo effects are notable demonstrations of mind–body interactions,. During pain
perception, in the absence of any treatment, an expectation of pain relief can reduce the …
perception, in the absence of any treatment, an expectation of pain relief can reduce the …
Thermal constraints on in vivo optogenetic manipulations
A key assumption of optogenetics is that light only affects opsin-expressing neurons.
However, illumination invariably heats tissue, and many physiological processes are …
However, illumination invariably heats tissue, and many physiological processes are …
Fluorescence imaging of large-scale neural ensemble dynamics
Recent progress in fluorescence imaging allows neuroscientists to observe the dynamics of
thousands of individual neurons, identified genetically or by their connectivity, across …
thousands of individual neurons, identified genetically or by their connectivity, across …
Burst-dependent synaptic plasticity can coordinate learning in hierarchical circuits
Synaptic plasticity is believed to be a key physiological mechanism for learning. It is well
established that it depends on pre-and postsynaptic activity. However, models that rely …
established that it depends on pre-and postsynaptic activity. However, models that rely …
A motivational and neuropeptidergic hub: anatomical and functional diversity within the nucleus accumbens shell
The mesocorticolimbic pathway is canonically known as the" reward pathway." Embedded
within the center of this circuit is the striatum, a massive and complex network hub that …
within the center of this circuit is the striatum, a massive and complex network hub that …
Striatal activity topographically reflects cortical activity
The cortex projects to the dorsal striatum topographically, to regulate behaviour,–, but
spiking activity in the two structures has previously been reported to have markedly different …
spiking activity in the two structures has previously been reported to have markedly different …
Updating the striatal–pallidal wiring diagram
The striatal and pallidal complexes are basal ganglia structures that orchestrate learning
and execution of flexible behavior. Models of how the basal ganglia subserve these …
and execution of flexible behavior. Models of how the basal ganglia subserve these …
Adaptive disinhibitory gating by VIP interneurons permits associative learning
Learning drives behavioral adaptations necessary for survival. While plasticity of excitatory
projection neurons during associative learning has been extensively studied, little is known …
projection neurons during associative learning has been extensively studied, little is known …