Single-cell sequencing (SCS) has impacted many areas of cancer research and improved
our understanding of intratumor heterogeneity, the tumor microenvironment, metastasis, and …

The analysis of circulating tumor cells (CTCs) is an outstanding tool to provide insights into
the biology of metastatic cancers, to monitor disease progression and with potential for use …

BACKGROUND. Liquid biopsies have demonstrated that the constitutively active androgen
receptor splice variant-7 (AR-V7) associates with reduced response and overall survival …

Circulating tumor cell (CTC)-based liquid biopsies provide unique opportunities for cancer
diagnostics, treatment selection, and response monitoring, but even with advanced …

Single-cell sequencing (SCS) is an emerging high-throughput technology that can be used
to study the genomics, transcriptomics, and epigenetics at a single cell level. SCS is widely …

Digital PCR (dPCR) is built on partitioning reagent to the extent that single template
molecules are amplified and visualized individually, whereby offers higher precision and …

Cancer is characterized by hypomethylation-associated silencing of large chromatin
domains, whose contribution to tumorigenesis is uncertain. Through high-resolution genome …

New sensitive assays are currently available for the detection of circulating tumor DNA
(ctDNA) and circulating tumor cells (CTC). However, there remains a need for …

Circulating tumor cells (CTCs) are rare tumor cells released from primary, metastatic, or
recurrent tumors in the peripheral blood of cancer patients. CTCs isolation from peripheral …

Circulating tumor cells (CTCs) are a rare subset of cells found in the blood of patients with
solid tumors, which function as a seed for metastases. Cancer cells metastasize through the …