[HTML][HTML] A systematic review informing the management of symptomatic brain radiation necrosis after stereotactic radiosurgery and international stereotactic …

B Vellayappan, MJ Lim-Fat, R Kotecha… - International Journal of …, 2024 - Elsevier
Background Radiation necrosis (RN) secondary to stereotactic radiosurgery is a significant
cause of morbidity. The optimal management of corticosteroid-refractory brain RN remains …

Treatment of central nervous system tumors on combination MR-linear accelerators: review of current practice and future directions

JM Bryant, A Doniparthi, J Weygand, R Cruz-Chamorro… - Cancers, 2023 - mdpi.com
Simple Summary Magnetic resonance imaging (MRI) has several advantages over
computerized tomography (CT) in the treatment planning of central nervous system (CNS) …

[HTML][HTML] Central nervous system metastases in advanced non-small cell lung cancer: A review of the therapeutic landscape central nervous system metastases in …

M Weller, J Remon, S Rieken, P Vollmuth, MJ Ahn… - Cancer treatment …, 2024 - Elsevier
Up to 40% of patients with non-small cell lung cancer (NSCLC) develop central nervous
system (CNS) metastases. Current treatments for this subgroup of patients with advanced …

Modern stereotactic radiotherapy for brain metastases from lung cancer: current trends and future perspectives based on integrated translational approaches

M Levis, A Gastino, G De Giorgi, C Mantovani… - Cancers, 2023 - mdpi.com
Simple Summary In the current era of precision medicine, the management of patients with
brain metastases (BMs) is rapidly evolving. The technical evolution of radiotherapy, now …

Stereotactic radiosurgery and stereotactic fractionated radiotherapy in the management of brain metastases

S Benkhaled, L Schiappacasse, A Awde, R Kinj - Cancers, 2024 - mdpi.com
Simple Summary The management of brain metastases (BM) is a major issue in cancer
treatment, and one of the main goals of BM treatment is to achieve effective disease control …

[PDF][PDF] Phase II multicenter trial combining nivolumab and radiosurgery for NSCLC and RCC brain metastases

P Wong, L Masucci, M Florescu… - Neuro-Oncology …, 2023 - academic.oup.com
Background Anti-PD-1 has activity in brain metastases (BM). This phase II open labeled non-
randomized single arm trial examined the safety and efficacy of combining nivolumab with …

Stereotactic radiosurgery for brain metastases from human epidermal receptor 2 positive breast Cancer: an international, multi-center study

S Pikis, G Mantziaris, M Protopapa, SM Tos… - Journal of Neuro …, 2024 - Springer
Purpose To report patient outcomes and local tumor control rates in a cohort of patients with
biopsy-proven HER-2 positive breast cancer treated with stereotactic radiosurgery (SRS) for …

Immune checkpoint inhibition and single fraction stereotactic radiosurgery in brain metastases from non-small cell lung cancer: an international multicenter study of …

EJ Lehrer, AA Khosla, A Ozair, J Gurewitz… - Journal of neuro …, 2023 - Springer
Purpose Approximately 80% of brain metastases originate from non-small cell lung cancer
(NSCLC). Immune checkpoint inhibitors (ICI) and stereotactic radiosurgery (SRS) are …

Combination of radiosurgery and immunotherapy in brain metastases: balance between efficacy and toxicities

A Botticella, F Dhermain - Current Opinion in Neurology, 2023 - journals.lww.com
The efficacy/toxicity balance of SRS-ICI combination should be regularly re-evaluated,
anticipating continued progress in ICI and SRS delivery, with more long-survivors potentially …