Rutin as a potent antioxidant: Implications for neurodegenerative disorders

AB Enogieru, W Haylett, DC Hiss… - Oxidative medicine …, 2018 - Wiley Online Library
A wide range of neurodegenerative diseases (NDs), including Alzheimer's disease,
Parkinson's disease, Huntington's disease, and prion diseases, share common mechanisms …

Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's …

DB Kell - Archives of toxicology, 2010 - Springer
Exposure to a variety of toxins and/or infectious agents leads to disease, degeneration and
death, often characterised by circumstances in which cells or tissues do not merely die and …

The crucial role of metal ions in neurodegeneration: the basis for a promising therapeutic strategy

A Gaeta, RC Hider - British journal of pharmacology, 2005 - Wiley Online Library
The variety of factors and events involved in neurodegeneration renders the subject a major
challenge. Neurodegenerative disorders include a number of different pathological …

Brain iron homeostasis: from molecular mechanisms to clinical significance and therapeutic opportunities

N Singh, S Haldar, AK Tripathi, K Horback… - Antioxidants & redox …, 2014 - liebertpub.com
Iron has emerged as a significant cause of neurotoxicity in several neurodegenerative
conditions, including Alzheimer's disease (AD), Parkinson's disease (PD), sporadic …

Analytical applications of Fourier transform-infrared (FT-IR) spectroscopy in microbiology and prion research

M Beekes, P Lasch, D Naumann - Veterinary microbiology, 2007 - Elsevier
A genuine biophysical method, Fourier transform-infrared (FT-IR) spectroscopy has become
a versatile research tool in biochemistry and biomedicine. Topical applications in …

A systems approach to prion disease

D Hwang, IY Lee, H Yoo, N Gehlenborg… - Molecular systems …, 2009 - embopress.org
Prions cause transmissible neurodegenerative diseases and replicate by conformational
conversion of normal benign forms of prion protein (PrPC) to disease‐causing PrPSc …

[HTML][HTML] Neurotoxicity of nanoscale materials

A Karmakar, Q Zhang, Y Zhang - Journal of Food and Drug Analysis, 2014 - Elsevier
Nanotechnology has been applied in consumer products and commercial applications,
showing a significant impact on almost all industries and all areas of society. Significant …

Biological inorganic and bioinorganic chemistry of neurodegeneration based on prion and Alzheimer diseases

DR Brown, H Kozlowski - Dalton Transactions, 2004 - pubs.rsc.org
A change of the prion protein conformation results in a class of neurodegenerative diseases
called the transmissible spongiform encephalopathies (like mad cow and Creutzfeld–Jakob …

Oxidative stress and the prion protein in transmissible spongiform encephalopathies

O Milhavet, S Lehmann - Brain research reviews, 2002 - Elsevier
Transmissible spongiform encephalopathies form a group of fatal neurodegenerative
disorders that have the unique property of being infectious, sporadic or genetic in origin …

Iron, neuroinflammation, and Alzheimer's disease

WY Ong, AA Farooqui - Journal of Alzheimer's Disease, 2005 - journals.sagepub.com
The present article reviews the roles and interactions of iron and neuroinflammation in
Alzheimer's disease. It highlights the importance of neuroinflammatory changes in the glial …