European Association of Urology guidelines on upper urinary tract urothelial carcinoma: 2023 update

M Rouprêt, T Seisen, AJ Birtle, O Capoun… - European urology, 2023 - Elsevier
Abstract Context The European Association of Urology (EAU) guidelines panel on upper
urinary tract urothelial carcinoma (UTUC) has updated the guidelines to aid clinicians in …

European Association of Urology guidelines on muscle-invasive and metastatic bladder cancer: summary of the 2020 guidelines

JA Witjes, HM Bruins, R Cathomas, EM Compérat… - European urology, 2021 - Elsevier
Context This overview presents the updated European Association of Urology (EAU)
guidelines for muscle-invasive and metastatic bladder cancer (MMIBC). Objective To …

[HTML][HTML] Nivolumab plus gemcitabine–cisplatin in advanced urothelial carcinoma

MS Van Der Heijden, G Sonpavde… - … England Journal of …, 2023 - Mass Medical Soc
Background No new agent has improved overall survival in patients with unresectable or
metastatic urothelial carcinoma when added to first-line cisplatin-based chemotherapy …

[HTML][HTML] Erdafitinib or chemotherapy in advanced or metastatic urothelial carcinoma

Y Loriot, N Matsubara, SH Park… - … England Journal of …, 2023 - Mass Medical Soc
Background Erdafitinib is a pan–fibroblast growth factor receptor (FGFR) inhibitor approved
for the treatment of locally advanced or metastatic urothelial carcinoma in adults with …

Treatment of muscle‐invasive and advanced bladder cancer in 2020

VG Patel, WK Oh, MD Galsky - CA: a cancer journal for …, 2020 - Wiley Online Library
Bladder cancer accounts for nearly 170,000 deaths worldwide annually. For over 4 decades,
the systemic management of muscle‐invasive and advanced bladder cancer has primarily …

Pembrolizumab alone or combined with chemotherapy versus chemotherapy as first-line therapy for advanced urothelial carcinoma (KEYNOTE-361): a randomised …

T Powles, T Csőszi, M Özgüroğlu, N Matsubara… - The Lancet …, 2021 - thelancet.com
Summary Background PD-1 and PD-L1 inhibitors are active in metastatic urothelial
carcinoma, but positive randomised data supporting their use as a first-line treatment are …

Pembrolizumab as second-line therapy for advanced urothelial carcinoma

J Bellmunt, R De Wit, DJ Vaughn… - … England Journal of …, 2017 - Mass Medical Soc
Background Patients with advanced urothelial carcinoma that progresses after platinum-
based chemotherapy have a poor prognosis and limited treatment options. Methods In this …

Atezolizumab in patients with locally advanced and metastatic urothelial carcinoma who have progressed following treatment with platinum-based chemotherapy: a …

JE Rosenberg, J Hoffman-Censits, T Powles… - The Lancet, 2016 - thelancet.com
Background Patients with metastatic urothelial carcinoma have few treatment options after
failure of platinum-based chemotherapy. In this trial, we assessed treatment with …

Bladder cancer

L Dyrskjøt, DE Hansel, JA Efstathiou… - Nature Reviews …, 2023 - nature.com
Bladder cancer is a global health issue with sex differences in incidence and prognosis.
Bladder cancer has distinct molecular subtypes with multiple pathogenic pathways …

Atezolizumab as first-line treatment in cisplatin-ineligible patients with locally advanced and metastatic urothelial carcinoma: a single-arm, multicentre, phase 2 trial

AV Balar, MD Galsky, JE Rosenberg, T Powles… - The Lancet, 2017 - thelancet.com
Background First-line chemotherapy for patients with cisplatin-ineligible locally advanced or
metastatic urothelial carcinoma is associated with short response duration, poor survival …