Ecology of anti-biofilm agents II: bacteriophage exploitation and biocontrol of biofilm bacteria

ST Abedon - Pharmaceuticals, 2015 - mdpi.com
Bacteriophages are the viruses of bacteria. In the guise of phage therapy they have been
used for decades to successfully treat what are probable biofilm-containing chronic bacterial …

Phage Paride can kill dormant, antibiotic-tolerant cells of Pseudomonas aeruginosa by direct lytic replication

E Maffei, AK Woischnig, MR Burkolter, Y Heyer… - Nature …, 2024 - nature.com
Bacteriophages are ubiquitous viral predators that have primarily been studied using fast-
growing laboratory cultures of their bacterial hosts. However, microbial life in nature is …

[HTML][HTML] Modeling tailed bacteriophage adsorption: Insight into mechanisms

ZJ Storms, D Sauvageau - Virology, 2015 - Elsevier
The process of a bacteriophage attaching to its host cell is a combination of physical
diffusion, biochemical surface interactions, and reaction-induced conformational changes in …

Slow growing bacteria survive bacteriophage in isolation

EL Attrill, U Łapińska, ER Westra… - ISME …, 2023 - academic.oup.com
The interactions between bacteria and bacteriophage have important roles in the global
ecosystem; in turn changes in environmental parameters affect the interactions between …

Energetic cost of building a virus

G Mahmoudabadi, R Milo… - Proceedings of the …, 2017 - National Acad Sciences
Viruses are incapable of autonomous energy production. Although many experimental
studies make it clear that viruses are parasitic entities that hijack the molecular resources of …

The gut environment regulates bacterial gene expression which modulates susceptibility to bacteriophage infection

M Lourenço, L Chaffringeon, Q Lamy-Besnier… - Cell Host & Microbe, 2022 - cell.com
Abundance and diversity of bacteria and their viral predators, bacteriophages (phages), in
the digestive tract are associated with human health. Particularly intriguing is the long-term …

Effect of bacterial growth rate on bacteriophage population growth rate

D Nabergoj, P Modic, A Podgornik - MicrobiologyOpen, 2018 - Wiley Online Library
It is important to understand how physiological state of the host influence propagation of
bacteriophages (phages), due to the potential higher phage production needs in the future …

Manufacturing of bacteriophages for therapeutic applications

J João, J Lampreia, DMF Prazeres, AM Azevedo - Biotechnology Advances, 2021 - Elsevier
Bacteriophages, or simply phages, are the most abundant biological entities on Earth. One
of the most interesting characteristics of these viruses, which infect and use bacteria as their …

[HTML][HTML] PhageScore: A simple method for comparative evaluation of bacteriophages lytic activity

M Konopacki, B Grygorcewicz, B Dołęgowska… - Biochemical …, 2020 - Elsevier
Nowadays, an increasing amount of studies indicate the numerous applications of
bacteriophages (eg medical, pharmaceutical, use in animal breeding, food processing) …

[HTML][HTML] Phage “delay” towards enhancing bacterial escape from biofilms: a more comprehensive way of viewing resistance to bacteriophages

ST Abedon - AIMS microbiology, 2017 - ncbi.nlm.nih.gov
In exploring bacterial resistance to bacteriophages, emphasis typically is placed on those
mechanisms which completely prevent phage replication. Such resistance can be detected …