The key differences between human papillomavirus-positive and-negative head and neck cancers: biological and clinical implications
SF Powell, L Vu, WC Spanos, D Pyeon - Cancers, 2021 - mdpi.com
Simple Summary Head and neck cancer (HNC) is the sixth most common cancer, causing
almost half a million deaths worldwide every year. The two subtypes of HNC are distinctly …
almost half a million deaths worldwide every year. The two subtypes of HNC are distinctly …
Assessment criteria and clinical implications of extranodal extension in head and neck cancer
SH Huang, R Chernock, B O'Sullivan… - American Society of …, 2021 - ascopubs.org
Tumor breaching the capsule of a lymph node is termed extranodal extension (ENE). It
reflects aggressiveness of a tumor, creates anatomic challenges for disease clearance, and …
reflects aggressiveness of a tumor, creates anatomic challenges for disease clearance, and …
Randomized trial of radiotherapy versus transoral robotic surgery for oropharyngeal squamous cell carcinoma: long-term results of the ORATOR trial
AC Nichols, J Theurer, E Prisman, N Read… - Journal of Clinical …, 2022 - ascopubs.org
PURPOSE The incidence of oropharyngeal squamous cell carcinoma (OPSCC) has risen
rapidly, because of an epidemic of human papillomavirus infection. The optimal …
rapidly, because of an epidemic of human papillomavirus infection. The optimal …
Cell‐free human papillomavirus DNA kinetics after surgery for human papillomavirus–associated oropharyngeal cancer
CJ O'Boyle, G Siravegna, S Varmeh, N Queenan… - Cancer, 2022 - Wiley Online Library
Background New ultrasensitive methods for detecting residual disease after surgery are
needed in human papillomavirus–associated oropharyngeal squamous cell carcinoma …
needed in human papillomavirus–associated oropharyngeal squamous cell carcinoma …
Time to surgery and survival in head and neck cancer
CJ Rygalski, S Zhao, A Eskander, KY Zhan… - Annals of surgical …, 2021 - Springer
Background The COVID-19 pandemic has required triage and delays in surgical care
throughout the world. The impact of these surgical delays on survival for patients with head …
throughout the world. The impact of these surgical delays on survival for patients with head …
Role of human papillomavirus infection in head and neck cancer in Italy: the HPV-AHEAD study
M Tagliabue, M Mena, F Maffini, T Gheit… - Cancers, 2020 - mdpi.com
Simple Summary This is the largest and most comprehensive assessment of the role of
human papillomavirus (HPV) in head and neck cancer (HNC) in Italy, which is a region …
human papillomavirus (HPV) in head and neck cancer (HNC) in Italy, which is a region …
Novel Strategies to Effectively De-escalate Curative-Intent Therapy for Patients With HPV-Associated Oropharyngeal Cancer: Current and Future Directions.
KAR Price, AC Nichols, CJ Shen… - American Society of …, 2020 - europepmc.org
The treatment of patients with HPV-associated oropharyngeal cancer (HPV-OPC) is rapidly
evolving and challenging the standard of care of definitive radiotherapy with concurrent …
evolving and challenging the standard of care of definitive radiotherapy with concurrent …
Increased rate of recurrence and high rate of salvage in patients with human papillomavirus–associated oropharyngeal squamous cell carcinoma with adverse …
Background Some patients with human papillomavirus (HPV)–associated oropharyngeal
squamous cell carcinoma (OPSCC) do not receive guideline‐recommended postoperative …
squamous cell carcinoma (OPSCC) do not receive guideline‐recommended postoperative …
Recurrent human papillomavirus–related head and neck cancer undergoes metabolic reprogramming and is driven by oxidative phosphorylation
A Vyas, RA Harbison, DL Faden, M Kubik… - Clinical Cancer …, 2021 - AACR
Purpose: Human papillomavirus (HPV) infection drives the development of some head and
neck squamous cell carcinomas (HNSCC). This disease is rapidly increasing in incidence …
neck squamous cell carcinomas (HNSCC). This disease is rapidly increasing in incidence …
All HPV-negative head and neck cancers are not the same: Analysis of the TCGA dataset reveals that anatomical sites have distinct mutation, transcriptome, hypoxia …
Purpose Head and neck squamous cell carcinoma (HNSCC) affects various anatomical
sites, which often dictates whether the cancer is managed with primary surgery or radiation …
sites, which often dictates whether the cancer is managed with primary surgery or radiation …