[HTML][HTML] Potential applications of plant biotechnology against SARS-CoV-2

T Capell, RM Twyman, V Armario-Najera, JKC Ma… - Trends in plant …, 2020 - cell.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel coronavirus
responsible for an ongoing human pandemic (COVID-19). There is a massive international …

Molecular farming–the slope of enlightenment

R Fischer, JF Buyel - Biotechnology advances, 2020 - Elsevier
Molecular farming can be defined as the use of plants to produce recombinant protein
products. The technology is now> 30 years old. The early promise of molecular farming was …

Regulatory approval and a first‐in‐human phase I clinical trial of a monoclonal antibody produced in transgenic tobacco plants

JKC Ma, J Drossard, D Lewis, F Altmann… - Plant biotechnology …, 2015 - Wiley Online Library
Although plant biotechnology has been widely investigated for the production of clinical‐
grade monoclonal antibodies, no antibody products derived from transgenic plants have yet …

Tomato (Solanum lycopersicum) health components: from the seed to the consumer

M Dorais, DL Ehret, AP Papadopoulos - Phytochemistry Reviews, 2008 - Springer
It is widely accepted that a healthy diet is an important factor in preventing chronic diseases,
and in improving energy balance and weight management. Studies have shown strong …

Plant volatiles: production, function and pharmacology

ME Maffei, J Gertsch, G Appendino - Natural product reports, 2011 - pubs.rsc.org
Covering: 1989 to February 2011 Plant volatiles typically occur as a complex mixture of low-
molecular weight lipophilic compounds derived from different biosynthetic pathways, and …

Advances in plant molecular farming

OO Obembe, JO Popoola, S Leelavathi… - Biotechnology advances, 2011 - Elsevier
Plant molecular farming (PMF) is a new branch of plant biotechnology, where plants are
engineered to produce recombinant pharmaceutical and industrial proteins in large …

[HTML][HTML] Biotechnological insights on the expression and production of antimicrobial peptides in plants

B Shanmugaraj, CJI Bulaon, A Malla, W Phoolcharoen - Molecules, 2021 - mdpi.com
The emergence of drug-resistant pathogens poses a serious critical threat to global public
health and requires immediate action. Antimicrobial peptides (AMPs) are a class of short …

[HTML][HTML] Molecular pharming—VLPs made in plants

J Marsian, GP Lomonossoff - Current opinion in biotechnology, 2016 - Elsevier
Highlights•Transient expression is an effective method for the production of VLPs in
plants.•A number of VLPs, consisting of one or more proteins, have been produced.•Plant …

Expression strategies for the efficient synthesis of antimicrobial peptides in plastids

MP Hoelscher, J Forner, S Calderone, C Krämer… - Nature …, 2022 - nature.com
Antimicrobial peptides (AMPs) kill microbes or inhibit their growth and are promising next-
generation antibiotics. Harnessing their full potential as antimicrobial agents will require …

Exhaustion of the chloroplast protein synthesis capacity by massive expression of a highly stable protein antibiotic

M Oey, M Lohse, B Kreikemeyer, R Bock - The plant journal, 2009 - Wiley Online Library
Plastids (chloroplasts) possess an enormous capacity to synthesize and accumulate foreign
proteins. Here we have maximized chloroplast protein production by over‐expressing a …