Recent advances in the medicinal chemistry of carbonic anhydrase inhibitors

S Kumar, S Rulhania, S Jaswal, V Monga - European Journal of Medicinal …, 2021 - Elsevier
Abstract Carbonic anhydrase (CA, EC 4.2. 1.1) is an enzyme and a very omnipresent zinc
metalloenzyme which catalyzed the reversible hydration and dehydration of carbon dioxide …

[HTML][HTML] Biomimetic mineralization for carbon capture and sequestration

Y Ma, S Yi, M Wang - Carbon Capture Science & Technology, 2024 - Elsevier
Carbon mineralization is an emerging field of research in carbon sequestration. In this
process, dissolved inorganic carbon reacts with mineral cations such as Ca 2+ and Mg 2+ to …

Membrane-separated reactor for an integrated CO2 capture-mineralization process using carbonic anhydrase

YH Ro, KY Kim, SK Jeong, GB Rhim, DH Moon… - Chemical Engineering …, 2023 - Elsevier
To achieve carbon neutrality through CO 2 mineralization, it is important to design the novel
reaction process through a distinct understanding of the critical reaction steps, CO 2 …

Identification and evaluation of glutathione conjugate gamma-l-glutamyl-l-cysteine for improved drug delivery to the brain

S Fatima, T Mohammad, DS Jairajpuri… - Journal of …, 2020 - Taylor & Francis
Glutathione (GU), an endogenous antioxidant tripeptide, is frequently transferred in the
human brain through N-methyl-d-aspartate receptor (NMDAR), profusely expressed at the …

Identification of high-affinity inhibitors of cyclin-dependent kinase 2 towards anticancer therapy

T Mohammad, S Batra, R Dahiya, MH Baig, IA Rather… - Molecules, 2019 - mdpi.com
Cyclin-dependent kinase 2 (CDK2) is an essential protein kinase involved in the cell cycle
regulation. The abnormal activity of CDK2 is associated with cancer progression and …

Enzymatic CO2 Capture in intensified packed-bed column bioreactors: A techno-economic assessment

K Nguyen, I Iliuta, LC Pasquier, F Bougie, MC Iliuta - Applied Energy, 2024 - Elsevier
To reduce the impact of industrial carbon dioxide (CO 2) emissions on climate change,
energy-efficient and cost-effective carbon capture technologies are needed. With this in …

Biological evaluation of p-toluene sulphonylhydrazone as carbonic anhydrase IX inhibitors: An approach to fight hypoxia-induced tumors

A Queen, P Khan, D Idrees, A Azam… - International journal of …, 2018 - Elsevier
To find potential inhibitors of human carbonic anhydrase IX (CAIX), we have successfully
deigned, synthesized and characterized three p-toluene sulphonylhydrazone derivatives (1 …

[HTML][HTML] Synthesis and utilisation of hybrid metal-carbonic anhydrase enzyme carrier system for soil biocementation

W Mwandira, D Purchase, M Mavroulidou, MJ Gunn - Applied Sciences, 2023 - mdpi.com
Biocementation is an emerging nature-inspired method of producing eco-friendly cement for
soil stabilization. This paper used the bovine-derived carbonic anhydrase (CA) enzyme to …

Effect of pH on the structure and stability of irisin, a multifunctional protein: Multispectroscopic and molecular dynamics simulation approach

R Waseem, A Shamsi, M Shahbaz, T Khan… - Journal of Molecular …, 2022 - Elsevier
Irisin is a potential therapeutic agent to prevent or treat various metabolic-related disorders
and neurodegenerative diseases viz. Alzheimer's disease (AD). In this study, we have …

Discovery of natural compounds as potential inhibitors of human carbonic anhydrase II: An integrated virtual screening, docking, and molecular dynamics simulation …

F Anjum, F Ali, T Mohammad, A Shafie… - OMICS: A Journal of …, 2021 - liebertpub.com
Carbonic anhydrase II (CAII) is one of the zinc metalloenzymes that catalyze the reversible
hydration of carbon dioxide, leading to the formation of bicarbonate and proton. CAII plays a …