Strategies to address low drug solubility in discovery and development
Drugs with low water solubility are predisposed to low and variable oral bioavailability and,
therefore, to variability in clinical response. Despite significant efforts to “design in” …
therefore, to variability in clinical response. Despite significant efforts to “design in” …
Micellar nanocarriers: pharmaceutical perspectives
VP Torchilin - Pharmaceutical research, 2007 - Springer
Micelles, self-assembling nanosized colloidal particles with a hydrophobic core and
hydrophilic shell are currently successfully used as pharmaceutical carriers for water …
hydrophilic shell are currently successfully used as pharmaceutical carriers for water …
[BOOK][B] Food emulsions: principles, practices, and techniques
DJ McClements - 2004 - taylorfrancis.com
Food Emulsions: Principles, Practice, and Techniques, Second Edition introduces the
fundamentals of emulsion science and demonstrates how this knowledge can be applied to …
fundamentals of emulsion science and demonstrates how this knowledge can be applied to …
Structure and design of polymeric surfactant-based drug delivery systems
VP Torchilin - Journal of controlled release, 2001 - Elsevier
The review concentrates on the use of polymeric micelles as pharmaceutical carriers.
Micellization of biologically active substances is a general phenomenon that increases the …
Micellization of biologically active substances is a general phenomenon that increases the …
Solubilization of membranes by detergents
30 membrane structure and function it is usually necessary to dissociate the membrane into
its components. The techniques for extraction and analysis of the membrane lipids are well …
its components. The techniques for extraction and analysis of the membrane lipids are well …
[BOOK][B] Catalysis in micellar and macromoleular systems
J Fendler - 2012 - books.google.com
Catalysis in Micellar and Macromolecular Systems provides a comprehensive monograph
on the catalyses elicited by aqueous and nonaqueous micelles, synthetic and naturally …
on the catalyses elicited by aqueous and nonaqueous micelles, synthetic and naturally …
Water solubility enhancement of some organic pollutants and pesticides by dissolved humic and fulvic acids
CT Chiou, RL Malcolm, TI Brinton… - Environmental science & …, 1986 - ACS Publications
Water solubility enhancements by dissolved humic and fulvic acids from soil and aquatic
origins and by synthetic organic polymers have been determined for selected or-ganic …
origins and by synthetic organic polymers have been determined for selected or-ganic …
Theory of surfactant self-assembly: a predictive molecular thermodynamic approach
A thermodynamic treatment of surfactant self-assembly in aqueous media is developed that
allows an a priori quantitative prediction of the aggregation behavior of surfactants, starting …
allows an a priori quantitative prediction of the aggregation behavior of surfactants, starting …
A century of dissolution research: from Noyes and Whitney to the biopharmaceutics classification system
Dissolution research started to develop about 100 years ago as a field of physical chemistry
and since then important progress has been made. However, explicit interest in drug related …
and since then important progress has been made. However, explicit interest in drug related …
[BOOK][B] Handbook of surface and colloid chemistry
KS Birdi - 2008 - taylorfrancis.com
The third edition of this besteller covers the latest advancements in this rapidly growing field.
Focusing on analyses and critical evaluation of the subject, this new edition reviews the …
Focusing on analyses and critical evaluation of the subject, this new edition reviews the …