Recent progress in chemosensors based on pyrazole derivatives
Colorimetric and fluorescent probes based on small organic molecules have become
important tools in modern biology because they provide dynamic information concerning the …
important tools in modern biology because they provide dynamic information concerning the …
Pyrazole Scaffolds: centrality in anti-inflammatory and antiviral drug design
Background: Pyrazole is a component of a diversity of bioactive heterocyclic congeners with
a broad-spectrum range of biological and pharmacological uses. Designing novel pyrazole …
a broad-spectrum range of biological and pharmacological uses. Designing novel pyrazole …
Synthesis of new magnetic nanocatalyst Fe3O4@CPTMO-phenylalanine-Ni and its catalytic effect in the preparation of substituted pyrazoles
S Bikas, A Poursattar Marjani, S Bibak… - Scientific Reports, 2023 - nature.com
In this study, a new, efficient and stable magnetically heterogeneous nanocatalyst of
Fe3O4@ CPTMO-phenylalanine-Ni via multi steps process starting from simple and cost …
Fe3O4@ CPTMO-phenylalanine-Ni via multi steps process starting from simple and cost …
Electrochemical synthesis of pyrazolines and pyrazoles via [3+ 2] dipolar cycloaddition
M Linden, S Hofmann, A Herman… - Angewandte Chemie …, 2023 - Wiley Online Library
Pyrazolines and pyrazoles are common and important motifs of pharmaceutical agents and
agrochemicals. Herein, the first electrochemical approach for their direct synthesis from …
agrochemicals. Herein, the first electrochemical approach for their direct synthesis from …
Development of novel bosentan analogues as endothelin receptor antagonists for pulmonary arterial hypertension
Since decades, bosentan has been in use for the treatment of pulmonary arterial
hypertension (PAH). However, chronic exposure to bosentan leads to the development of …
hypertension (PAH). However, chronic exposure to bosentan leads to the development of …
Synthesis, biological screening and in silico studies of new N-phenyl-4-(1, 3-diaryl-1H-pyrazol-4-yl) thiazol-2-amine derivatives as potential antifungal and …
Y Nandurkar, MR Bhoye, D Maliwal… - European Journal of …, 2023 - Elsevier
A new series of N-aryl-4-(1, 3-diaryl-1H-pyrazol-4-yl) thiazol-2-amine,(8a-x) have been
synthesized by a cyclo-condensation reaction of 2-bromo-1-(1, 3-diphenyl-1H-pyrazol-4-yl) …
synthesized by a cyclo-condensation reaction of 2-bromo-1-(1, 3-diphenyl-1H-pyrazol-4-yl) …
Experimental and theoretical tests on the corrosion protection of mild steel in hydrochloric acid environment by the use of pyrazole derivative
In this study, 1, 5-diallyl-1H-pyrazolo [3, 4-d] pyrimidin-4 (5H)-one (PPD) was evaluated as
an anticorrosion agent for mild steel (MS) in 1 M HCl. The analysis was performed by weight …
an anticorrosion agent for mild steel (MS) in 1 M HCl. The analysis was performed by weight …
Applications of oxone® in organic synthesis: an emerging green reagent of modern era
Presently, the major cornerstone of the research community is to develop green as well as
sustainable protocols involving inexpensive catalysts and/or reagents without the usage of …
sustainable protocols involving inexpensive catalysts and/or reagents without the usage of …
Berotralstat (BCX7353): structure-guided design of a potent, selective, and oral plasma kallikrein inhibitor to prevent attacks of hereditary angioedema (HAE)
PL Kotian, M Wu, S Vadlakonda… - Journal of Medicinal …, 2021 - ACS Publications
Hereditary angioedema (HAE) is a rare and potentially life-threatening disease that affects
an estimated 1 in 50 000 individuals worldwide. Until recently, prophylactic HAE treatment …
an estimated 1 in 50 000 individuals worldwide. Until recently, prophylactic HAE treatment …
Synthesis of 1, 3, 5-trisubstituted pyrazoles via 1, 3-dipolar cycloaddition of nitrile imines with ninhydrin-derived Morita–Baylis–Hillman carbonates
KK Wang, YL Li, J **g, R Chen, NN Zhao… - Organic & …, 2022 - pubs.rsc.org
An effective synthetic method for 1, 3, 5-trisubstituted pyrazoles via 1, 3-dipolar cycloaddition
reaction has been developed. This reaction could smoothly proceed between ninhydrin …
reaction has been developed. This reaction could smoothly proceed between ninhydrin …