Alzheimer's Disease and Vascular Aging: JACC Focus Seminar

M Cortes-Canteli, C Iadecola - Journal of the American College of …, 2020 - jacc.org
Alzheimer's disease, the leading cause of dementia in the elderly, is a neurodegenerative
condition characterized by accumulation of amyloid plaques and neurofibrillary tangles in …

The impact of disease comorbidities in Alzheimer's disease

JA Santiago, JA Potashkin - Frontiers in aging neuroscience, 2021 - frontiersin.org
A wide range of comorbid diseases is associated with Alzheimer's disease (AD), the most
common neurodegenerative disease worldwide. Evidence from clinical and molecular …

Neutrophil counts and cardiovascular disease

J Luo, JQ Thomassen, BG Nordestgaard… - European Heart …, 2023 - academic.oup.com
Abstract Background and Aims Anti-inflammatory trials have shown considerable benefits for
cardiovascular disease. High neutrophil counts, an easily accessible inflammation …

Valorizing the usage of olive leaves, bioactive compounds, biological activities, and food applications: A comprehensive review

S Selim, M Albqmi, MM Al-Sanea, TS Alnusaire… - Frontiers in …, 2022 - frontiersin.org
Olive oil production is a significant source of economic profit for Mediterranean nations,
accounting for around 98 percent of global output. Olive oil usage has increased …

ApoE4: an emerging therapeutic target for Alzheimer's disease

M Safieh, AD Korczyn, DM Michaelson - BMC medicine, 2019 - Springer
Background The growing body of evidence indicating the heterogeneity of Alzheimer's
disease (AD), coupled with disappointing clinical studies directed at a fit-for-all therapy …

[HTML][HTML] Prevention of dementia in an ageing world: Evidence and biological rationale

G Grande, C Qiu, L Fratiglioni - Ageing research reviews, 2020 - Elsevier
As the population ages, the number of people with dementia is expected to increase in the
coming decades, with consequences at the societal and individual levels. In this narrative …

Relation of cerebral vessel disease to Alzheimer's disease dementia and cognitive function in elderly people: a cross-sectional study

Z Arvanitakis, AW Capuano, SE Leurgans… - The Lancet …, 2016 - thelancet.com
Background Few data on the pathology of cerebral vessel disease, dementia, and cognition
are available. We examined the association of cerebral atherosclerosis and …

[HTML][HTML] Pathophysiologic relationship between Alzheimer's disease, cerebrovascular disease, and cardiovascular risk: a review and synthesis

CY Santos, PJ Snyder, WC Wu, M Zhang… - Alzheimer's & Dementia …, 2017 - Elsevier
As the population ages due to demographic trends and gains in life expectancy, the
incidence and prevalence of dementia increases, and the need to understand the etiology …

[HTML][HTML] Shared risk factors between dementia and atherosclerotic cardiovascular disease

LT Nordestgaard, M Christoffersen… - International Journal of …, 2022 - mdpi.com
Alzheimer's disease is the most common form of dementia, and the prodromal phases of
Alzheimer's disease can last for decades. Vascular dementia is the second most common …

Tau induces blood vessel abnormalities and angiogenesis-related gene expression in P301L transgenic mice and human Alzheimer's disease

RE Bennett, AB Robbins, M Hu, X Cao… - Proceedings of the …, 2018 - pnas.org
Mixed pathology, with both Alzheimer's disease and vascular abnormalities, is the most
common cause of clinical dementia in the elderly. While usually thought to be concurrent …