Circadian rhythms are 24-h cycles regulated by endogeneous molecular oscillators called
the circadian clock. The effects of diet on circadian rhythmicity clearly involves a relationship …

Modulation of basic biochemical and physiological processes by the circadian timing system
is now recognized as a fundamental feature of all mammalian organ systems. Within the …

In mammals, circadian control of physiology and behavior is driven by a master pacemaker
located in the suprachiasmatic nuclei (SCN) of the hypothalamus. We have used gene …

▪ Abstract The core apparatus that regulates circadian rhythm has been extensively studied
over the past five years. A looming question remains, however, regarding how this …

Background Fatigue is experienced by most patients with multiple sclerosis (MS) and often
is profoundly debilitating. No large-scale studies to our knowledge have examined circadian …

Mammalian circadian rhythms of activity are generated within the suprachiasmatic nucleus
(SCN). Transcripts from the imprinted, paternally expressed Magel2 gene, which maps to the …

Pineal melatonin is synthesized and secreted in close association with the light/dark cycle.
The temporal relationship between the nocturnal rise in melatonin secretion and the …

Circadian clock genes are regulated through a transcriptional-translational feedback loop.
Alterations of the chromatin structure by histone acetyltransferases and histone …

Circadian rhythm sleep‐wake disorders (CRSWD s) are characterized by persistent or
recurrent patterns of sleep disturbance related primarily to alterations of the circadian rhythm …

The circadian timing system (CTS) in mammals may be defined as a network of
interconnected diencephalic structures that regulate the timing of physiological processes …