RNA is becoming more important as an increasing number of functions, both regulatory and
enzymatic, are being discovered on a daily basis. As the RNA boom has just begun, most …

An ever‐increasing number of functional RNAs require a mechanistic understanding. RNA
function relies on changes in its structure, so‐called dynamics. To reveal dynamic processes …

The synthetic neomycin‐sensing riboswitch interacts with its cognate ligand neomycin as
well as with the related antibiotics ribostamycin and paromomycin. Binding of these …

MicroRNAs (miRNAs) regulate the levels of translation of messenger RNAs (mRNAs). At
present, the major parameter that can explain the selection of the target mRNA and the …

This review describes off-resonance R 1ρ relaxation dispersion NMR methods for
characterizing microsecond-to-millisecond chemical exchange in uniformly 13 C/15 N …

Proteins and nucleic acids are highly dynamic bio-molecules that can populate a variety of
conformational states. NMR relaxation dispersion (RD) methods are uniquely suited to …

Recent studies have shown that RNAs exist in dynamic equilibrium with short-lived low-
abundance 'excited states' that form by reshuffling base pairs in and around non-canonical …

The knowledge of structure and dynamics is crucial to explain the function of RNAs. While
nuclear magnetic resonance (NMR) is well suited to probe these for complex biomolecules …

The HIV-1 Rev response element (RRE) RNA element mediates the nuclear export of intron
containing viral RNAs by forming an oligomeric complex with the viral protein Rev. Stem IIB …

Recent findings in genome-wide transcriptomics revealed that RNAs are involved in almost
every biological process, across all domains of life. The characterization of native RNAs of …