Next-generation sequencing: insights to advance clinical investigations of the microbiome
CR Wensel, JL Pluznick, SL Salzberg… - The Journal of clinical …, 2022 - Am Soc Clin Investig
Next-generation sequencing (NGS) technology has advanced our understanding of the
human microbiome by allowing for the discovery and characterization of unculturable …
human microbiome by allowing for the discovery and characterization of unculturable …
Mass spectrometry-based metabolomics in microbiome investigations
A Bauermeister, H Mannochio-Russo… - Nature Reviews …, 2022 - nature.com
Microbiotas are a malleable part of ecosystems, including the human ecosystem.
Microorganisms affect not only the chemistry of their specific niche, such as the human gut …
Microorganisms affect not only the chemistry of their specific niche, such as the human gut …
MicrobiomeAnalyst 2.0: comprehensive statistical, functional and integrative analysis of microbiome data
Microbiome studies have become routine in biomedical, agricultural and environmental
sciences with diverse aims, including diversity profiling, functional characterization, and …
sciences with diverse aims, including diversity profiling, functional characterization, and …
Multi-level analysis of the gut–brain axis shows autism spectrum disorder-associated molecular and microbial profiles
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by
heterogeneous cognitive, behavioral and communication impairments. Disruption of the gut …
heterogeneous cognitive, behavioral and communication impairments. Disruption of the gut …
Greengenes2 unifies microbial data in a single reference tree
Studies using 16S rRNA and shotgun metagenomics typically yield different results, usually
attributed to PCR amplification biases. We introduce Greengenes2, a reference tree that …
attributed to PCR amplification biases. We introduce Greengenes2, a reference tree that …
DS-1000: A natural and reliable benchmark for data science code generation
We introduce DS-1000, a code generation benchmark with a thousand data science
problems spanning seven Python libraries, such as Numpy and Pandas. Compared to prior …
problems spanning seven Python libraries, such as Numpy and Pandas. Compared to prior …
A gut-derived metabolite alters brain activity and anxiety behaviour in mice
Integration of sensory and molecular inputs from the environment shapes animal behaviour.
A major site of exposure to environmental molecules is the gastrointestinal tract, in which …
A major site of exposure to environmental molecules is the gastrointestinal tract, in which …
The UNITE database for molecular identification and taxonomic communication of fungi and other eukaryotes: sequences, taxa and classifications reconsidered
Abstract UNITE (https://unite. ut. ee) is a web-based database and sequence management
environment for molecular identification of eukaryotes. It targets the nuclear ribosomal …
environment for molecular identification of eukaryotes. It targets the nuclear ribosomal …
The microbiome-derived metabolite TMAO drives immune activation and boosts responses to immune checkpoint blockade in pancreatic cancer
The composition of the gut microbiome can control innate and adaptive immunity and has
emerged as a key regulator of tumor growth, especially in the context of immune checkpoint …
emerged as a key regulator of tumor growth, especially in the context of immune checkpoint …
Gut microbiota from green tea polyphenol-dosed mice improves intestinal epithelial homeostasis and ameliorates experimental colitis
Z Wu, S Huang, T Li, N Li, D Han, B Zhang, ZZ Xu… - Microbiome, 2021 - Springer
Background Alteration of the gut microbiota may contribute to the development of
inflammatory bowel disease (IBD). Epigallocatechin-3-gallate (EGCG), a major bioactive …
inflammatory bowel disease (IBD). Epigallocatechin-3-gallate (EGCG), a major bioactive …