Abstract γ-Aminobutyric acid (GABA) is the major inhibitory neurotransmitter released at
GABAergic synapses, mediating fast-acting phasic inhibition. Emerging lines of evidence …

The cerebellar cortex is an important system for relating neural circuits and learning. Its
promise reflects the longstanding idea that it contains simple, repeated circuit modules with …

While classical views of cerebellar learning have suggested that this structure predominantly
operates according to an error-based supervised learning rule to refine movements …

Precision pharmacology aims to manipulate specific cellular interactions within complex
tissues. In this pursuit, we introduce DART. 2 (drug acutely restricted by tethering), a second …

The cerebellum is a central brain structure deeply integrated into major loops with the
cerebral cortex, brainstem, and spinal cord. The cerebellum shows a complex regional …

GABA transporters belong to a large family of neurotransmitter: sodium symporters. They are
widely expressed throughout the brain, with different levels of expression in different brain …

Cortical inhibitory neurons exhibit remarkable diversity in their morphology, connectivity, and
synaptic properties. Here, we review the function of somatostatin-expressing (SOM) …

Subjective tinnitus is the conscious perception of sound in the absence of any acoustic
source. The literature suggests various tinnitus mechanisms, most of which invoke changes …

The ability of the brain to rapidly process information from multiple pathways is critical for
reliable execution of complex sensory-motor behaviors, yet the cellular mechanisms …

Pattern separation is a fundamental function of the brain. The divergent feedforward
networks thought to underlie this computation are widespread, yet exhibit remarkably similar …