Cocrystals have gained attention in the pharmaceutical industry due to their ability to
improve solubility, stability, in vitro dissolution rate, and bioavailability of poorly soluble …

This article describes the synthesis and characterization of new cocrystals of ciprofloxacin
with nicotinic and isonicotinic acids as coformers. The cocrystals were obtained by a …

This work reports the mechanochemical synthesis and characterization of a cocrystal formed
by norfloxacin (NOR) and nicotinic acid (NCA). The thermal analysis provided the thermal …

Cocrystals are recognized as one of the most efficient approaches to improve aqueous
solubility of Biopharmaceutical Classification System, BCS, classes II and IV drugs …

Novel cocrystals of ciprofloxacin with pyrazinoic acid and p-aminobenzoic acid in the 1: 1
stoichiometric ratio were obtained by the mechanochemical method, under conditions of …

Cocrystals have wide applicability in the field of pharmaceutical sciences, promoting
improvements in the physicochemical properties of the drugs. Trans-cinnamic acid (TCA) is …

The Schröeder-van Laar equation to predict the theoretical eutectic melting temperature
values was applied to a set of fourteen binary mixtures (UR1 to UR14). The fourteen binary …

Stability is an important parameter to evaluate the quality, safety and efficacy of drug
substances and pharmaceutical products. The stability studies aim to determine the ability of …

Certainly, most chemistry students, patients or simply curious, have already questioned
themselves about certain medications present in their daily lives, trying to understand how …

In this study, single crystals of L-tryptophan-fumaric acid-water (LTFAW) were obtained
using the slow solvent evaporation method, while LTFAW polycrystals were synthesized by …