Recovery from disorders of consciousness: mechanisms, prognosis and emerging therapies

BL Edlow, J Claassen, ND Schiff… - Nature Reviews Neurology, 2021 - nature.com
Substantial progress has been made over the past two decades in detecting, predicting and
promoting recovery of consciousness in patients with disorders of consciousness (DoC) …

Therapeutic interventions in patients with prolonged disorders of consciousness

A Thibaut, N Schiff, J Giacino, S Laureys… - The Lancet …, 2019 - thelancet.com
The management of patients with severe brain injuries and prolonged disorders of
consciousness raises important issues particularly with respect to their therapeutic options …

European Academy of Neurology guideline on the diagnosis of coma and other disorders of consciousness

D Kondziella, A Bender, K Diserens… - European journal of …, 2020 - Wiley Online Library
Background and purpose Patients with acquired brain injury and acute or prolonged
disorders of consciousness (DoC) are challenging. Evidence to support diagnostic decisions …

Robust EEG-based cross-site and cross-protocol classification of states of consciousness

DA Engemann, F Raimondo, JR King, B Rohaut… - Brain, 2018 - academic.oup.com
Determining the state of consciousness in patients with disorders of consciousness is a
challenging practical and theoretical problem. Recent findings suggest that multiple markers …

Are there levels of consciousness?

T Bayne, J Hohwy, AM Owen - Trends in cognitive sciences, 2016 - cell.com
The notion of a level of consciousness is a key construct in the science of consciousness.
Not only is the term employed to describe the global states of consciousness that are …

Early detection of consciousness in patients with acute severe traumatic brain injury

BL Edlow, C Chatelle, CA Spencer, CJ Chu, YG Bodien… - Brain, 2017 - academic.oup.com
Abstract See Schiff (doi: 10.1093/awx209) for a scientific commentary on this article. Patients
with acute severe traumatic brain injury may recover consciousness before self-expression …

Clinical and advanced neurophysiology in the prognostic and diagnostic evaluation of disorders of consciousness: review of an IFCN-endorsed expert group

A Comanducci, M Boly, J Claassen, M De Lucia… - Clinical …, 2020 - Elsevier
The analysis of spontaneous EEG activity and evoked potentials is a cornerstone of the
instrumental evaluation of patients with disorders of consciousness (DoC). The past few …

Disorders of consciousness after acquired brain injury: the state of the science

JT Giacino, JJ Fins, S Laureys, ND Schiff - Nature Reviews Neurology, 2014 - nature.com
The concept of consciousness continues to defy definition and elude the grasp of
philosophical and scientific efforts to formulate a testable construct that maps to human …

Brain networks predict metabolism, diagnosis and prognosis at the bedside in disorders of consciousness

S Chennu, J Annen, S Wannez, A Thibaut, C Chatelle… - Brain, 2017 - academic.oup.com
Recent advances in functional neuroimaging have demonstrated novel potential for
informing diagnosis and prognosis in the unresponsive wakeful syndrome and minimally …

Preserved consciousness in vegetative and minimal conscious states: systematic review and meta-analysis

D Kondziella, CK Friberg, VG Frokjaer… - Journal of Neurology …, 2016 - jnnp.bmj.com
Active, passive and resting state paradigms using functional MRI (fMRI) or EEG may reveal
consciousness in the vegetative (VS) and the minimal conscious state (MCS). A meta …