History shows that metal-based drugs and remedies have been known and used since very
ancient times. For example, silver was employed in the treatment of wounds and ulcers …

This review focuses on cytotoxic rhenium compounds in terms of IC 50 values, their mode of
action in biological systems and their status in clinical trials. Biological studies of different …

Seven rhenium (I) complexes of the general formula fac-[Re (CO) 3 (NN)(OH2)]+ where NN=
2, 2′-bipyridine (8), 4, 4′-dimethyl-2, 2′-bipyridine (9), 4, 4′-dimethoxy-2, 2′-bipyridine …

Here, we have synthesized and characterized three visible light responsive terpyridine
based-Re (I)-tricarbonyl complexes;[Re (CO) 3 (ph-tpy) Cl](Retp1),[Re (CO) 3 (an-tpy) …

Background: Many rhenium (Re) complexes with potential anticancer properties have been
synthesized in the recent years with the aim to overcome the clinical limitations of platinum …

Mitochondria play a critical role in tumorigenesis. Targeting mitochondria and disturbing
related events have been emerging as a promising way for chemotherapy. In this work, two …

Rhenium (V) oxo complexes of general formula [ReO (OMe)(N^ N) Cl2], where N^ N= 4, 7-
diphenyl-1, 10-phenanthroline, 1, or 3, 4, 7, 8-tetramethyl-1, 10-phenanthroline, 2, effectively …

The established platinum-based drugs form covalent DNA adducts to elicit their cytotoxic
response. Although they are widely employed, these agents cause toxic side-effects and are …

A series of luminescent monometallic fac-[Re (bipy)(CO) 3 (L)]+ and heterometallic fac-[Re
(bipy)(CO) 3 (L-AuPPh3)]+ complexes, where L is an imidazole, alkynyl-imidazole or alkynyl …

Chemotherapy with the cytotoxic platinum (Pt) drugs cisplatin, carboplatin, and oxaliplatin is
the mainstay of anticancer therapy in the clinic. The antitumor activity of Pt drugs originates …