Effects of surgery and anesthetic choice on immunosuppression and cancer recurrence

R Kim - Journal of translational medicine, 2018 - Springer
Background The relationship between surgery and anesthetic-induced immunosuppression
and cancer recurrence remains unresolved. Surgery and anesthesia stimulate the …

[HTML][HTML] Influence of perioperative anaesthetic and analgesic interventions on oncological outcomes: a narrative review

T Wall, A Sherwin, D Ma, DJ Buggy - British journal of anaesthesia, 2019 - Elsevier
Surgery is an important treatment modality for the majority of solid organ cancers.
Unfortunately, cancer recurrence following surgery of curative intent is common, and …

[PDF][PDF] Perioperative anesthetic strategies and their impact on cancer recurrence and immune function

I Karunarathna, K De Alvis, P Gunasena… - 2024 - researchgate.net
Oncological surgery and anesthesia both stimulate the hypothalamic-pituitary-adrenal (HPA)
axis and the sympathetic nervous system (SNS). The HPA axis suppresses the host immune …

[PDF][PDF] Effects of anesthesia and analgesia on immunomodulation and cancer recurrence: A review

I Karunarathna, K De Alvis, P Gunasena… - 2024 - researchgate.net
Oncological surgery and anesthesia both stimulate the hypothalamic-pituitary-adrenal (HPA)
axis and the sympathetic nervous system (SNS). The HPA axis suppresses the host immune …

[HTML][HTML] Anesthetic technique and cancer outcomes: a meta-analysis of total intravenous versus volatile anesthesia

A Yap, MA Lopez-Olivo, J Dubowitz, J Hiller… - Canadian Journal of …, 2019 - infona.pl
Purpose Cancer-related mortality, a leading cause of death worldwide, is often the result of
metastatic disease recurrence. Anesthetic techniques have varying effects on innate and …

Effect of anaesthetic technique on the natural killer cell anti-tumour activity of serum from women undergoing breast cancer surgery: a pilot study

A Buckley, S McQuaid, P Johnson… - British Journal of …, 2014 - academic.oup.com
Background Animal models and retrospective clinical data suggest that certain anaesthetic
techniques can attenuate immunosuppression and minimize metastasis after cancer …

Distinct effects of general anesthetics on lung metastasis mediated by IL-6/JAK/STAT3 pathway in mouse models

R Li, Y Huang, J Lin - Nature communications, 2020 - nature.com
Metastasis can occur following surgical resection of solid tumors and metastasis is the main
cause of cancer death. The role of anesthetics used during surgery in cancer metastasis and …

Effects of propofol/remifentanil-based total intravenous anesthesia versus sevoflurane-based inhalational anesthesia on the release of VEGF-C and TGF-β and …

T Yan, GH Zhang, BN Wang, L Sun, H Zheng - BMC anesthesiology, 2018 - Springer
Background Vascular endothelial growth factor (VEGF) and transforming growth factor-β
(TGF-β) have been involved in tumor growth and metastasis. Sevoflurane may promote …

The effect of propofol and sevoflurane on cancer cell, natural killer cell, and cytotoxic T lymphocyte function in patients undergoing breast cancer surgery: an in vitro …

JA Lim, CS Oh, TG Yoon, JY Lee, SH Lee, YB Yoo… - BMC cancer, 2018 - Springer
Background To clarify the effect of anaesthetic agents on cancer immunity, we evaluated the
effects of propofol and sevoflurane on natural killer (NK) cell, cytotoxic T lymphocyte (CTL) …

Implicating anaesthesia and the perioperative period in cancer recurrence and metastasis

JA Dubowitz, EK Sloan, BJ Riedel - Clinical & experimental metastasis, 2018 - Springer
Cancer, currently the leading cause of death in the population aged less than 85 years,
poses a significant global disease burden and is anticipated to continue to increase in …