RNA helicases are ubiquitous, highly conserved enzymes that participate in nearly all
aspects of RNA metabolism. These proteins bind or remodel RNA or RNA–protein …

Group II introns are mobile ribozymes that self-splice from precursor RNAs to yield excised
intron lariat RNAs, which then invade new genomic DNA sites by reverse splicing. The …

The prokaryotic CRISPR/Cas immune system is based on genomic loci that contain
incorporated sequence tags from viruses and plasmids. Using small guide RNA molecules …

Superfamily 2 helicase proteins are ubiquitous in RNA biology and have an extraordinarily
broad set of functional roles. Central among these roles are the promotion of …

DEAD-box proteins, the largest helicase family, catalyze ATP-dependent remodeling of RNA–
protein complexes and the unwinding of RNA duplexes. Because DEAD-box proteins …

DEAD‐box proteins are ubiquitous in RNA‐mediated processes and function by coupling
cycles of ATP binding and hydrolysis to changes in affinity for single‐stranded RNA. Many …

Retrotransposons mobilize via RNA intermediates and usually carry with them the agent of
their mobility, reverse transcriptase. Retrotransposons are streamlined, and therefore rely on …

DEAD box proteins catalyze the ATP-dependent unwinding of double-stranded RNA
(dsRNA). In addition, they facilitate protein displacement and remodeling of RNA or …

The yeast DEAD box protein Mss116p is a general RNA chaperone that functions in
mitochondrial group I and II intron splicing, translational activation, and RNA end …

DEAD-box proteins represent the largest family of RNA helicases, present in all three
kingdoms of life. They are involved in a variety of processes involving RNA metabolism and …