Wnt signaling pathway in rheumatoid arthritis, with special emphasis on the different roles in synovial inflammation and bone remodeling
C Miao, Y Yang, X He, X Li, C Huang, Y Huang… - Cellular signalling, 2013 - Elsevier
Rheumatoid arthritis (RA) is a chronic symmetrical autoimmune disease of unknown etiology
that affects primarily the diarthrodial joints. Characteristic features of RA pathogenesis are …
that affects primarily the diarthrodial joints. Characteristic features of RA pathogenesis are …
The underlying pathophysiology and therapeutic approaches for osteoporosis
H Awasthi, D Mani, D Singh… - Medicinal research …, 2018 - Wiley Online Library
With an increase in the ageing population worldwide, the prevalence of osteoporosis
increases at an alarming rate in both male and female irrespective of their ethnicity. At …
increases at an alarming rate in both male and female irrespective of their ethnicity. At …
Pathogenesis of Paget disease of bone
SH Ralston, R Layfield - Calcified tissue international, 2012 - Springer
Paget disease of bone (PDB) is a common disease characterized by focal areas of
increased and disorganized bone turnover. Some patients are asymptomatic, whereas …
increased and disorganized bone turnover. Some patients are asymptomatic, whereas …
[HTML][HTML] A monoclonal antibody against the Wnt signaling inhibitor dickkopf-1 inhibits osteosarcoma metastasis in a preclinical model
SD Goldstein, M Trucco, WB Guzman, M Hayashi… - Oncotarget, 2016 - ncbi.nlm.nih.gov
The outcome of patients with metastatic osteosarcoma has not improved since the
introduction of chemotherapy in the 1970s. Development of therapies targeting the …
introduction of chemotherapy in the 1970s. Development of therapies targeting the …
A model for the pathogenesis of bisphosphonate-associated osteonecrosis of the jaw and teriparatide's potential role in its resolution
G Subramanian, HV Cohen, SYP Quek - Oral Surgery, Oral Medicine, Oral …, 2011 - Elsevier
OBJECTIVE: The objective of this study was to present a comprehensive model for the
pathogenesis of bisphosphonate-associated osteonecrosis of the jaw (BON). STUDY …
pathogenesis of bisphosphonate-associated osteonecrosis of the jaw (BON). STUDY …
Glucocorticoids affect the metabolism of bone marrow stromal cells and lead to osteonecrosis of the femoral head: a review
T Gang, P KANG, F PEI - Chinese medical journal, 2012 - journals.lww.com
Glucocorticoids affect the metabolism of bone marrow stromal... : Chinese Medical Journal
Glucocorticoids affect the metabolism of bone marrow stromal cells and lead to osteonecrosis of …
Glucocorticoids affect the metabolism of bone marrow stromal cells and lead to osteonecrosis of …
Generation and selection of novel fully human monoclonal antibodies that neutralize Dickkopf-1 (DKK1) inhibitory function in vitro and increase bone mass in vivo
H Glantschnig, RA Hampton, P Lu, JZ Zhao… - Journal of Biological …, 2010 - ASBMB
Wnt/LRP5 signaling is a central regulatory component of bone formative and resorptive
activities, and the pathway inhibitor DKK1 is a suppressor of bone formation and bone mass …
activities, and the pathway inhibitor DKK1 is a suppressor of bone formation and bone mass …
Wnt1 Neuroprotection Translates into Improved Neurological Function during Oxidant Stress and Cerebral Ischemia Through AKT1 and Mitochondrial Apoptotic …
ZZ Chong, YC Shang, J Hou… - Oxidative medicine and …, 2010 - Wiley Online Library
Although essential for the development of the nervous system, Wnt1 also has been
associated with neurodegenerative disease and cognitive loss during periods of oxidative …
associated with neurodegenerative disease and cognitive loss during periods of oxidative …
Identification of differentially expressed microRNAs involved in non-traumatic osteonecrosis through microRNA expression profiling
X Wu, Y Zhang, X Guo, H Xu, Z Xu, D Duan, K Wang - Gene, 2015 - Elsevier
Accumulating evidence has recently indicated a vital role of microRNAs (miRNAs) in the
development of various bone diseases. However, the biological role of miRNAs in the …
development of various bone diseases. However, the biological role of miRNAs in the …
Emerging strategies and therapies for treatment of Paget's disease of bone
Paget's disease of bone (PDB) is a progressive monostotic or polyostotic metabolic bone
disease characterized by focal abnormal bone remodeling, with increased bone resorption …
disease characterized by focal abnormal bone remodeling, with increased bone resorption …