Arginine methylation is a common post-translational modification functioning as an
epigenetic regulator of transcription and playing key roles in pre-mRNA splicing, DNA …

Methylation of arginine residues by protein arginine methyltransferases (PRMTs) is involved
in the regulation of fundamental cellular processes, including transcription, RNA processing …

Protein methylation, a post-translational modification (PTM), is observed in a wide variety of
cell types from prokaryotes to eukaryotes. With recent and rapid advancements in epigenetic …

Addition of chemical tags on the DNA and modification of histone proteins impart a distinct
feature on chromatin architecture. With the advancement in scientific research, the key …

Arginine methylation is an influential post-translational modification occurring on histones,
RNA binding proteins, and many other cellular proteins, affecting their function by altering …

Abstract Protein arginine methyltransferase-5 (PRMT5) is reported to have a role in diverse
cellular processes, including tumorigenesis, and its overexpression is observed in cell lines …

Post-translational modification (PTM) of proteins is vital for increasing proteome diversity
and maintaining cellular homeostasis. If the writing, reading, and removal of modifications …

Numerous substrates have been identified for Type I and II arginine methyltransferases
(PRMTs). However, the full substrate spectrum of the only type III PRMT, PRMT7, and its …

Post-translational modifications of histones by protein methyltransferases (PMTs) and
histone demethylases (KDMs) play an important role in the regulation of gene expression …

As a predominant type II protein arginine methyltransferase, PRMT5 plays critical roles in
various normal cellular processes by catalyzing the mono-and symmetrical dimethylation of …