Therapeutic evolution of benzimidazole derivatives in the last quinquennial period
Benzimidazole, a fused heterocycle bearing benzene and imidazole has gained
considerable attention in the field of contemporary medicinal chemistry. The moiety is of …
considerable attention in the field of contemporary medicinal chemistry. The moiety is of …
[HTML][HTML] A review on benzimidazole heterocyclic compounds: Synthesis and their medicinal activity applications
LA Mohammed, MA Farhan, SA Dadoosh… - …, 2023 - thieme-connect.com
Benzimidazole is a heterocyclic compound that contains two nitrogen atoms and is formed
by fusing a benzene ring with an imidazole. Benzimidazole and its derivatives are prepared …
by fusing a benzene ring with an imidazole. Benzimidazole and its derivatives are prepared …
Design, synthesis, characterization, molecular docking studies and anticancer activity evaluation of novel hydrazinecarbothioamide, 1, 2, 4-triazole-3-thione, 4 …
ED Dincel, Ç Akdağ, T Kayra, ED Coşar… - Journal of Molecular …, 2022 - Elsevier
A series of novel hydrazinecarbothioamide, 1, 2, 4-triazole-3-thione, 4-thiazolidinone and 1,
3, 4-oxadiazole derivatives were synthesized and evaluated for their cytotoxic activity …
3, 4-oxadiazole derivatives were synthesized and evaluated for their cytotoxic activity …
Synthesis of stable benzimidazole derivatives bearing pyrazole as anticancer and EGFR receptor inhibitors
A new series of benzimidazole linked pyrazole derivatives were synthesized by
cyclocondensation reaction through one-pot multicomponent reaction in absolute ethanol …
cyclocondensation reaction through one-pot multicomponent reaction in absolute ethanol …
Synthesis, molecular modelling studies and ADME prediction of benzothiazole clubbed oxadiazole-Mannich bases, and evaluation of their anti-diabetic activity …
A small library of new benzothiazole clubbed oxadiazole-Mannich bases (M-1 to M-22) were
synthesized and characterized by IR, NMR, Mass and Elemental analysis results. Molecular …
synthesized and characterized by IR, NMR, Mass and Elemental analysis results. Molecular …
Design, synthesis, characterization and antimicrobial evaluation of some novel hydrazinecarbothioamide, 4‐thiazolidinone and 1, 2, 4‐triazole‐3‐thione derivatives
A series of novel hydrazinecarbothioamide (5a, c, f), 4‐thiazolidinone (6a‐e), and 1, 2, 4‐
triazole‐3‐thione (7a‐d) were designed and synthesized. The structural elucidations of the …
triazole‐3‐thione (7a‐d) were designed and synthesized. The structural elucidations of the …
A review on the synthesis and applications of molecules as anticonvulsant drug agent candidates
Epilepsy is one of the most common neurological disorders worldwide and it requires a long-
term or life-long treatment. Current standard treatment includes the use of antiepileptic …
term or life-long treatment. Current standard treatment includes the use of antiepileptic …
Suppression of isoproterenol-induced cardiotoxicity in rats by raspberry ketone via activation of peroxisome proliferator activated receptor-α
The peroxisome proliferator-activated receptor-α (PPAR-α) controls the lipid and glucose
metabolism and also affects inflammation, cell proliferation and apoptosis during …
metabolism and also affects inflammation, cell proliferation and apoptosis during …
Benzimidazole based hybrids against complex diseases: A catalogue of the SAR profile
The fused heterocyclic ring system has been recognized as a privileged structure that is
used as a template in medicinal chemistry for drug discovery. Benzimidazole is one of the …
used as a template in medicinal chemistry for drug discovery. Benzimidazole is one of the …
Design, synthesis, biological evaluation, molecular docking, and dynamic simulation study of novel imidazo [2, 1-b] thiazole derivatives as potent antioxidant agents
A series of novel hydrazinecarbothioamide and 1, 2, 4-triazole-3-thione derivatives of
imidazo [2, 1-b] thiazole were synthesized and evaluated for their antioxidant activity. The …
imidazo [2, 1-b] thiazole were synthesized and evaluated for their antioxidant activity. The …