Mammalian skeletal muscle comprises different fiber types, whose identity is first established
during embryonic development by intrinsic myogenic control mechanisms and is later …

Obesity can cause a decline in contractile function of skeletal muscle, thereby reducing
mobility and promoting obesity-associated health risks. We reviewed the literature to …

Fluorescence has long been recognized as a powerful tool for probing biological structure
and function. Nearly sixty-five years ago, Coons and colleagues introduced the first …

Muscle fibres have different properties with respect to force, contraction speed, endurance,
oxidative/glycolytic capacity etc. Although adult muscle fibres are normally post‐mitotic with …

A variety of fiber types with different contractile and metabolic properties is present in
mammalian skeletal muscle. The fiber-type profile is controlled by nerve activity via specific …

Skeletal muscles, being one of the most abundant tissues in the body, are involved in many
vital processes, such as locomotion, posture maintenance, respiration, glucose …

Inhibiting glycogen synthase kinase 3 (GSK3) improves muscle function, metabolism, and
bone health in many diseases and conditions; however, whether GSK3 should be targeted …

Key points Inactivation of a skeletal muscle results in slow to fast myosin heavy chain
(MyHC) shift. AMP‐activated protein kinase (AMPK) can be implicated in the regulation of …

Calcineurin is a Ca2+‐dependent serine/threonine phosphatase that dephosphorylates
nuclear factor of activated T cells (NFAT), allowing for NFAT entry into the nucleus. In …

A mammalian soleus muscle along with other “axial” muscles ensures the stability of the
body under the Earth's gravity. In rat experiments with hindlimb suspension, zero-gravity …