The evolving landscape of expanded carrier screening: challenges and opportunities

SA Kraft, D Duenas, BS Wilfond, KAB Goddard - Genetics in Medicine, 2019 - nature.com
Carrier screening allows individuals to learn their chance of passing on an autosomal or X-
linked condition to their offspring. Initially introduced as single-disease, ancestry-based …

Recent developments in genetics and medically-assisted reproduction: from research to clinical applications

JC Harper, K Aittomäki, P Borry… - Human …, 2017 - academic.oup.com
Two leading European professional societies, the European Society of Human Genetics and
the European Society for Human Reproduction and Embryology, have worked together …

Feasibility of couple-based expanded carrier screening offered by general practitioners

J Schuurmans, E Birnie, LM van den Heuvel… - European Journal of …, 2019 - nature.com
Expanded carrier screening (ECS) aims to inform couples' reproductive choice, preferably
before conception. As part of an implementation study in which trained general practitioners …

The more you do it, the easier it gets: using behaviour change theory to support health care professionals offering reproductive genetic carrier screening

S Best, JC Long, Z Fehlberg, T Theodorou… - European Journal of …, 2023 - nature.com
Recent advances in genomic sequencing have improved the accessibility of reproductive
genetic carrier screening (RGCS). As awareness and interest grows, non-genetic health …

Current updates on expanded carrier screening: new insights in the omics era

I Veneruso, C Di Resta, R Tomaiuolo, V D'Argenio - Medicina, 2022 - mdpi.com
Genetic carrier screening has been successfully used over the last decades to identify
individuals at risk of transmitting specific DNA variants to their newborns, thus having an …

Health practitioners' perceptions of the barriers and enablers to the implementation of reproductive genetic carrier screening: A systematic review

S Best, J Long, T Theodorou, S Hatem… - Prenatal …, 2021 - Wiley Online Library
Background As interest in reproductive genetic carrier screening rises, with increased
availability, the role of healthcare practitioners is central in guiding uptake aligned with a …

[HTML][HTML] The views of people with a lived experience of deafness and the general public regarding genetic testing for deafness in the reproductive setting: A systematic …

L Freeman, S Righetti, MB Delatycki, JL Scully… - Genetics in Medicine, 2022 - Elsevier
Purpose Genes associated with nonsyndromic hearing loss are commonly included in
reproductive carrier screening panels, which are now routinely offered in preconception and …

Stakeholder perspectives on the implementation of genetic carrier screening in a changing landscape

KCA Holtkamp, EM Vos, T Rigter, P Lakeman… - BMC Health Services …, 2017 - Springer
Background In most countries, genetic carrier screening is neither offered, nor embedded in
mainstream healthcare. Technological developments have triggered a two-fold transition in …

The uptake of pan‐ethnic expanded carrier screening is higher when offered during preconception or early prenatal genetic counseling

D Larsen, J Ma, M Strassberg… - Prenatal …, 2019 - Wiley Online Library
Objective To examine factors that influence uptake of expanded carrier screening (ECS)
among women undergoing preconception and prenatal genetic counseling. Methods We …

Expanded carrier screening: a current survey of physician utilization and attitudes

A Briggs, PK Nouri, M Galloway, K O'Leary… - Journal of Assisted …, 2018 - Springer
Purpose Expanded carrier screening (ECS) is an available component of preconception and
prenatal care. There is complexity around offering, administering, and following-up test …