Prospects and challenges for cell-cultured fat as a novel food ingredient

KD Fish, NR Rubio, AJ Stout, JSK Yuen… - Trends in food science & …, 2020 - Elsevier
Background In vitro meat production has been proposed as a solution to environmental and
animal welfare issues associated with animal agriculture. While most academic work on cell …

Human embryonic stem cell cultivation: historical perspective and evolution of xeno-free culture systems

N Desai, P Rambhia, A Gishto - Reproductive Biology and Endocrinology, 2015 - Springer
Human embryonic stem cells (hESC) have emerged as attractive candidates for cell-based
therapies that are capable of restoring lost cell and tissue function. These unique cells are …

[KNIHA][B] Culture of animal cells: a manual of basic technique and specialized applications

RI Freshney - 2015 - books.google.com
Since the publication of the sixth edition of this benchmark text, numerous advances in the
field have been made–particularly in stem cells, 3D culture, scale-up, STR profiling, and …

Defined essential 8™ medium and vitronectin efficiently support scalable xeno-free expansion of human induced pluripotent stem cells in stirred microcarrier culture …

SM Badenes, TG Fernandes, CSM Cordeiro… - PloS one, 2016 - journals.plos.org
Human induced pluripotent stem (hiPS) cell culture using Essential 8™ xeno-free medium
and the defined xeno-free matrix vitronectin was successfully implemented under adherent …

Scalable stirred suspension culture for the generation of billions of human induced pluripotent stem cells using single‐use bioreactors

CK Kwok, Y Ueda, A Kadari, K Günther… - Journal of tissue …, 2018 - Wiley Online Library
The production of human induced pluripotent stem cells (hiPSCs) in quantities that are
relevant for cell‐based therapies and cell‐loaded implants through standard adherent …

Microcarrier-based platforms for in vitro expansion and differentiation of human pluripotent stem cells in bioreactor culture systems

SM Badenes, TG Fernandes, CAV Rodrigues… - Journal of …, 2016 - Elsevier
Human pluripotent stem cells (hPSC) have attracted a great attention as an unlimited source
of cells for cell therapies and other in vitro biomedical applications such as drug screening …

Critical analysis of cGMP large-scale expansion process in bioreactors of human induced pluripotent stem cells in the framework of quality by design

A Rivera-Ordaz, V Peli, P Manzini, M Barilani, L Lazzari - BioDrugs, 2021 - Springer
Human induced pluripotent stem cells (hiPSCs) are manufactured as advanced therapy
medicinal products for tissue replacement applications. With this aim, the feasibility of hiPSC …

Emerging methods for enhancing pluripotent stem cell expansion

SW Chan, M Rizwan, EKF Yim - Frontiers in Cell and Developmental …, 2020 - frontiersin.org
Pluripotent stem cells (PSCs) have great potential to revolutionize the fields of tissue
engineering and regenerative medicine as well as stem cell therapeutics. However, the end …

A concise review on induced pluripotent stem cell-derived cardiomyocytes for personalized regenerative medicine

P Pushp, DES Nogueira, CAV Rodrigues… - Stem cell reviews and …, 2021 - Springer
The induced pluripotent stem cells (iPSCs) are derived from somatic cells by using
reprogramming factors such as Oct4, Sox2, Klf4, and c-Myc (OSKM) or Oct4, Sox2, Nanog …

Long‐term expansion of human induced pluripotent stem cells in a microcarrier‐based dynamic system

SM Badenes, TG Fernandes… - Journal of Chemical …, 2017 - Wiley Online Library
BACKGROUND Human induced pluripotent stem (hiPS) cells provide a fascinating tool for
exploring disease mechanisms, compound screening in pharmaceutical drug development …