Hydrogels in the treatment of rheumatoid arthritis: Drug delivery systems and artificial matrices for dynamic in vitro models
Rheumatoid arthritis (RA) is an autoimmune and chronic inflammatory disorder that mostly
affects the synovial joints and can promote both cartilage and bone tissue destruction …
affects the synovial joints and can promote both cartilage and bone tissue destruction …
Recent trends in stimuli-responsive hydrogels for the management of rheumatoid arthritis
Rheumatoid arthritis (RA) is a chronic inflammatory condition triggered by abnormal
autoimmune responses. Key characteristics of RA include the deterioration of joints and …
autoimmune responses. Key characteristics of RA include the deterioration of joints and …
Comparative study of liposomes, ethosomes and transfersomes as carriers for enhancing the transdermal delivery of diflunisal: in vitro and in vivo evaluation
The current study aimed to develop an effective transdermal nanovesicular carrier of
diflunisal that provides enhanced delivery through the skin. Two types of nanovesicles …
diflunisal that provides enhanced delivery through the skin. Two types of nanovesicles …
Penetration enhancing effects of selected natural oils utilized in topical dosage forms
Context: Various natural products, including oils, have been utilized as penetration
enhancers due to their “safety profiles”. These oils contain fatty acids promoting skin …
enhancers due to their “safety profiles”. These oils contain fatty acids promoting skin …
Diflunisal targeted delivery systems: A review
P Snetkov, S Morozkina, R Olekhnovich… - Materials, 2021 - mdpi.com
Diflunisal is a well-known drug for the treatment of rheumatoid arthritis, osteoarthritis,
primary dysmenorrhea, and colon cancer. This molecule belongs to the group of …
primary dysmenorrhea, and colon cancer. This molecule belongs to the group of …
Following-up skin penetration of lidocaine from different vehicles by Raman spectroscopic map**
M Bakonyi, A Gácsi, A Kovács, MB Szűcs… - … of Pharmaceutical and …, 2018 - Elsevier
The application of local anesthetics, usually administered by subcutaneous injection, is
common in the course of diagnostic, therapeutic, and cosmetic dermatology procedures. The …
common in the course of diagnostic, therapeutic, and cosmetic dermatology procedures. The …
A safe bioadhesive system for topical delivery of combined antimicrobials in treatment of skin infections in veterinary medicine
E Türkmen, S Parmaksız, Ş Nigiz, M Sağıroğlu… - Journal of Drug Delivery …, 2023 - Elsevier
Bacterial and fungal skin infections are common both in humans and animals, especially in
companion animals such as cats and dogs. Use of systemic antimicrobial drugs for the …
companion animals such as cats and dogs. Use of systemic antimicrobial drugs for the …
A comparative study of chitosan and poloxamer based thermosensitive hydrogel for the delivery of PEGylated melphalan conjugates
Objective: Although the melphalan (ML) used extensively for the management of breast
cancer, its clinical application is limited due to significant hemolytic activity. In the present …
cancer, its clinical application is limited due to significant hemolytic activity. In the present …
CD44-targeted hyaluronic acid coated imiquimod lipid nanocapsules foster the efficacy against skin cancer: Attempt to conquer unfavorable side effects
This study was executed to mitigate imiquimod (IMQ)-side effects and promote its anticancer
potential against skin cancer via encapsulation in hyaluronic acid-coated lipid nanocapsules …
potential against skin cancer via encapsulation in hyaluronic acid-coated lipid nanocapsules …
Follicular mediated etodolac phosalosomal gel for contact dermatitis alleviation, insights from optimization to in-vivo appraisal
Despite its long history as a preferential cyclooxygenase-2 inhibitor, the topical application
of etodolac in inflammatory disorders does not achieve the desired clinical efficiency …
of etodolac in inflammatory disorders does not achieve the desired clinical efficiency …