Large-vessel vasculitis

D Pugh, M Karabayas, N Basu, MC Cid… - Nature Reviews …, 2021 - nature.com
Large-vessel vasculitis (LVV) manifests as inflammation of the aorta and its major branches
and is the most common primary vasculitis in adults. LVV comprises two distinct conditions …

Disease-modifying anti-rheumatic drugs for the management of Takayasu arteritis—a systematic review and meta-analysis

DP Misra, U Rathore, P Patro, V Agarwal… - Clinical Rheumatology, 2021 - Springer
The pharmacotherapy of Takayasu arteritis (TAK) with disease-modifying anti-rheumatic
drugs (DMARDs) is an evolving area. A systematic review of Scopus, Web of Science …

The effectiveness of tocilizumab and its comparison with tumor necrosis factor alpha inhibitors for Takayasu arteritis: a systematic review and meta-analysis

DP Misra, K Singh, U Rathore, P Patro, A Tomelleri… - Autoimmunity …, 2023 - Elsevier
Takayasu arteritis (TAK) refractory to conventional disease-modifying anti-rheumatic drugs
(DMARDs) is commonly treated with biologic DMARDs such as tocilizumab or tumor …

Management of Takayasu arteritis

DP Misra, K Singh, U Rathore… - Best Practice & …, 2023 - Elsevier
This review overviews the challenges in the assessment of disease activity, damage, and
therapy of Takayasu arteritis (TAK). Recently developed disease activity scores for TAK are …

Novel Th17 lymphocyte populations, Th17. 1 and PD1+ Th17, are increased in Takayasu arteritis, and both Th17 and Th17. 1 sub-populations associate with active …

K Singh, U Rathore, MK Rai, MR Behera… - Journal of …, 2022 - Taylor & Francis
Purpose We evaluated T helper lymphocyte profile, including novel Th17 subsets Th17. 1
(secrete IFN-γ, associate with corticosteroid resistance) and PD1+ Th17 (secrete TGF-β1 …

Corticosteroid monotherapy for the management of Takayasu arteritis—a systematic review and meta-analysis

DP Misra, U Rathore, P Patro, V Agarwal… - Rheumatology …, 2021 - Springer
We evaluated clinical response, normalization of inflammatory markers, angiographic
stabilization (primary outcomes), relapses and adverse events (secondary outcomes) in …

Arterial wall fibrosis in Takayasu arteritis and its potential for therapeutic modulation

DP Misra, K Singh, A Sharma, V Agarwal - Frontiers in Immunology, 2023 - frontiersin.org
Arterial wall damage in Takayasu arteritis (TAK) can progress despite immunosuppressive
therapy. Vascular fibrosis is more prominent in TAK than in giant cell arteritis (GCA). The …

[HTML][HTML] Outcome measures and biomarkers for disease assessment in Takayasu arteritis

DP Misra, N Jain, M Ora, K Singh, V Agarwal… - Diagnostics, 2022 - mdpi.com
Takayasu arteritis (TAK) is a less common large vessel vasculitis where histopathology of
involved arteries is difficult to access except during open surgical procedures. Assessment …

[HTML][HTML] Comparison of presentation and prognosis of Takayasu arteritis with or without stroke or transient ischemic attack—a retrospective cohort study

DP Misra, U Rathore, P Mishra, K Singh, DR Thakare… - Life, 2022 - mdpi.com
Takayasu arteritis (TAK) could cause a stroke or transient ischemic attack (TIA) in young
individuals due to inflammatory vascular occlusion or intracerebral hemorrhage. We …

A systematic review of clinical and preclinical evidences for Janus kinase inhibitors in large vessel vasculitis

U Rathore, DR Thakare, P Patro, V Agarwal… - Clinical …, 2022 - Springer
Corticosteroid-sparing disease-modifying anti-rheumatic drugs are an area of active
exploration in large vessel vasculitis (LVV), ie, Takayasu arteritis (TAK) and Giant Cell …