Intracellular delivery by membrane disruption: mechanisms, strategies, and concepts

MP Stewart, R Langer, KF Jensen - Chemical reviews, 2018 - ACS Publications
Intracellular delivery is a key step in biological research and has enabled decades of
biomedical discoveries. It is also becoming increasingly important in industrial and medical …

A review on macroscale and microscale cell lysis methods

M Shehadul Islam, A Aryasomayajula… - Micromachines, 2017 - mdpi.com
The lysis of cells in order to extract the nucleic acids or proteins inside it is a crucial unit
operation in biomolecular analysis. This paper presents a critical evaluation of the various …

Microfluidic electroporation-facilitated synthesis of erythrocyte membrane-coated magnetic nanoparticles for enhanced imaging-guided cancer therapy

L Rao, B Cai, LL Bu, QQ Liao, SS Guo, XZ Zhao… - ACS …, 2017 - ACS Publications
Biomimetic cell membrane-coated nanoparticles (CM-NPs) with superior biochemical
properties have been broadly utilized for various biomedical applications. Currently …

Recent advances in microscale electroporation

SE Choi, H Khoo, SC Hur - Chemical reviews, 2022 - ACS Publications
Electroporation (EP) is a commonly used strategy to increase cell permeability for
intracellular cargo delivery or irreversible cell membrane disruption using electric fields. In …

The use of skin models in drug development

SH Mathes, H Ruffner, U Graf-Hausner - Advanced drug delivery reviews, 2014 - Elsevier
Three dimensional (3D) tissue models of the human skin are probably the most developed
and understood in vitro engineered constructs. The motivation to accomplish organotypic …

[HTML][HTML] In vitro electroporation detection methods–An overview

TB Napotnik, D Miklavčič - Bioelectrochemistry, 2018 - Elsevier
Exposing cells to an electric field leads to electroporation of the cell membrane which has
already been explored and used in a number of applications in medicine and food …

Recent advances in the use of microfluidic technologies for single cell analysis

TW Murphy, Q Zhang, LB Naler, S Ma, C Lu - Analyst, 2018 - pubs.rsc.org
The inherent heterogeneity in cell populations has become of great interest and importance
as analytical techniques have improved over the past decades. With the advent of …

Microfluidic electroporation for cellular analysis and delivery

T Geng, C Lu - Lab on a Chip, 2013 - pubs.rsc.org
Electroporation is a simple yet powerful technique for breaching the cell membrane barrier.
The applications of electroporation can be generally divided into two categories: the release …

Microfluidic and nanofluidic intracellular delivery

J Hur, AJ Chung - Advanced Science, 2021 - Wiley Online Library
Innate cell function can be artificially engineered and reprogrammed by introducing
biomolecules, such as DNAs, RNAs, plasmid DNAs, proteins, or nanomaterials, into the …

Electroporation of cell membranes: the fundamental effects of pulsed electric fields in food processing

G Saulis - Food Engineering Reviews, 2010 - Springer
Using of pulsed electric fields (PEF) for killing of microorganisms in liquid foods is a
promising new non-thermal food processing and preservation technology. However, to …