Synthetic biomarkers: a twenty-first century path to early cancer detection
Detection of cancer at an early stage when it is still localized improves patient response to
medical interventions for most cancer types. The success of screening tools such as cervical …
medical interventions for most cancer types. The success of screening tools such as cervical …
Mesenchymal stem cell exosomes
MSCs are an extensively used cell type in clinical trials today. The initial rationale for their
clinical testing was based on their differentiation potential. However, the lack of correlation …
clinical testing was based on their differentiation potential. However, the lack of correlation …
Spheroid culture of mesenchymal stem cells
Z Cesarz, K Tamama - Stem cells international, 2016 - Wiley Online Library
Compared with traditional 2D adherent cell culture, 3D spheroidal cell aggregates, or
spheroids, are regarded as more physiological, and this technique has been exploited in the …
spheroids, are regarded as more physiological, and this technique has been exploited in the …
Stem cell membrane, stem cell-derived exosomes and hybrid stem cell camouflaged nanoparticles: A promising biomimetic nanoplatforms for cancer theranostics
Nanomedicine research has advanced dramatically in recent decades. Nonetheless,
traditional nanomedicine faces significant obstacles such as the low concentration of the …
traditional nanomedicine faces significant obstacles such as the low concentration of the …
[HTML][HTML] Galectin 3 as a guardian of the tumor microenvironment
PP Ruvolo - Biochimica et Biophysica Acta (BBA)-Molecular Cell …, 2016 - Elsevier
Galectin 3 is a member of a family of β-galactoside binding proteins and has emerged as an
important regulator of diverse functions critical in cancer biology including apoptosis …
important regulator of diverse functions critical in cancer biology including apoptosis …
Differential effects of extracellular vesicles secreted by mesenchymal stem cells from different sources on glioblastoma cells
A Del Fattore, R Luciano, R Saracino… - Expert opinion on …, 2015 - Taylor & Francis
Background: Malignant glial tumors, including glioblastoma multiforme, account for 15–20%
of pediatric CNS malignancies. They are most resistant to therapy and are associated with a …
of pediatric CNS malignancies. They are most resistant to therapy and are associated with a …
MSCs derived from iPSCs with a modified protocol are tumor-tropic but have much less potential to promote tumors than bone marrow MSCs
Mesenchymal stem or stromal cells (MSCs) have many potential therapeutic applications
including therapies for cancers and tissue damages caused by cancers or radical cancer …
including therapies for cancers and tissue damages caused by cancers or radical cancer …
Adipose-derived Mesenchymal Stem Cells (ASCs) may favour breast cancer recurrence via HGF/c-Met signaling
V Eterno, A Zambelli, L Pavesi, L Villani, V Zanini… - …, 2013 - pmc.ncbi.nlm.nih.gov
Adipose tissue is a reservoir of Mesenchymal Stem Cells (Adipose-derived Mesenchymal
Stem Cells, ASCs), endowed with regenerative properties. Fat graft was proposed for breast …
Stem Cells, ASCs), endowed with regenerative properties. Fat graft was proposed for breast …
Cell-based nanoparticles delivery systems for targeted cancer therapy: lessons from anti-angiogenesis treatments
P de la Torre, MJ Pérez-Lorenzo, Á Alcázar-Garrido… - Molecules, 2020 - mdpi.com
The main strategy of cancer treatment has focused on attacking the tumor cells. Some
cancers initially responsive to chemotherapy become treatment-resistant. Another strategy is …
cancers initially responsive to chemotherapy become treatment-resistant. Another strategy is …
The immunomodulatory effects of mesenchymal stem cell polarization within the tumor microenvironment niche
CM Rivera-Cruz, JJ Shearer… - Stem cells …, 2017 - Wiley Online Library
Mesenchymal stem cells (MSCs) represent a promising tool for cell therapy, particularly for
their antitumor effects. This cell population can be isolated from multiple tissue sources and …
their antitumor effects. This cell population can be isolated from multiple tissue sources and …