Diazo groups have broad and tunable reactivity. That and other attributes endow diazo
compounds with the potential to be valuable reagents for chemical biologists. The presence …

Abstract “Chemistry has become a mature science, with all the advantages and handicaps of
maturity: harvest is abundant, but many people think future and adventure are to be found …

Photoaffinity labeling (PAL) in combination with a chemical probe to covalently bind its target
upon UV irradiation has demonstrated considerable promise in drug discovery for identifying …

This volume is an extended account of a group of techniques that have seen their
importance realized in almost all areas of biochemistry. The book provides detailed …

A new approach has been developed for the study of model and natural biomembranes.
This involves the cross-linking of diacetylene groups after ultraviolet irradiation. For the study …

The synthesis and some of the photochemical properties of 4'-(l-azi-2, 2, 2-trifluoroethyl)
phenylalanine (7, ATEPhe), a photolabile analogue of phenylalanine, are described. Upon …

Polymer chemists as poachers in foreign grounds? Why not? Macromolecular chemistry has
become a mature science with all advantages and handicaps of a well-established scientific …

Analogues of fatty acids have been synthesized which contain an SS bridge in the aliphatic
chain and at the omega-carbon the photoactivatable p-(3-trifluoromethyldiazirino) phenyl or …

The synthesis and characterization of a great variety of single and double chain
phospholipids containing the diacetylene and butadiene moiety is described. These …

A systematic study of the photoalkylation of amino acids by benzophenone, a standard
photosensitive probe of biomolecules, was performed addressing for the first time chemo …