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[HTML][HTML] Magnetic resonance imaging techniques for the quantitative analysis of skeletal muscle: State of the art
Background Magnetic resonance imaging (MRI) is the dominant 3D imaging modality to
quantify muscle properties in skeletal muscle disorders, in inherited and acquired muscle …
quantify muscle properties in skeletal muscle disorders, in inherited and acquired muscle …
Quantifying fat replacement of muscle by quantitative MRI in muscular dystrophy
J Burakiewicz, CDJ Sinclair, D Fischer, GA Walter… - Journal of …, 2017 - Springer
The muscular dystrophies are rare orphan diseases, characterized by progressive muscle
weakness: the most common and well known is Duchenne muscular dystrophy which affects …
weakness: the most common and well known is Duchenne muscular dystrophy which affects …
Detection of collagens by multispectral optoacoustic tomography as an imaging biomarker for Duchenne muscular dystrophy
AP Regensburger, LM Fonteyne, J Jüngert… - Nature medicine, 2019 - nature.com
Biomarkers for monitoring of disease progression and response to therapy are lacking for
muscle diseases such as Duchenne muscular dystrophy. Noninvasive in vivo molecular …
muscle diseases such as Duchenne muscular dystrophy. Noninvasive in vivo molecular …
MRI biomarker assessment of neuromuscular disease progression: a prospective observational cohort study
Background A substantial impediment to progress in trials of new therapies in
neuromuscular disorders is the absence of responsive outcome measures that correlate with …
neuromuscular disorders is the absence of responsive outcome measures that correlate with …
The pathogenesis and therapy of muscular dystrophies
Current molecular genomic approaches to human genetic disorders have led to an
explosion in the identification of the genes and their encoded proteins responsible for these …
explosion in the identification of the genes and their encoded proteins responsible for these …
Skeletal muscle quantitative nuclear magnetic resonance imaging and spectroscopy as an outcome measure for clinical trials
Recent years have seen tremendous progress towards therapy of many previously incurable
neuromuscular diseases. This new context has acted as a driving force for the development …
neuromuscular diseases. This new context has acted as a driving force for the development …
Multicenter prospective longitudinal study of magnetic resonance biomarkers in a large duchenne muscular dystrophy cohort
Objective The aim of this study was to describe Duchenne muscular dystrophy (DMD)
disease progression in the lower extremity muscles over 12 months using quantitative …
disease progression in the lower extremity muscles over 12 months using quantitative …
MRI in neuromuscular diseases: an emerging diagnostic tool and biomarker for prognosis and efficacy
There is an unmet need to identify biomarkers sensitive to change in rare, slowly
progressive neuromuscular diseases. Quantitative magnetic resonance imaging (MRI) of …
progressive neuromuscular diseases. Quantitative magnetic resonance imaging (MRI) of …
MR biomarkers predict clinical function in Duchenne muscular dystrophy
Objective To investigate the potential of lower extremity magnetic resonance (MR)
biomarkers to serve as endpoints in clinical trials of therapeutics for Duchenne muscular …
biomarkers to serve as endpoints in clinical trials of therapeutics for Duchenne muscular …
Muscle MRI in muscular dystrophies
Muscle MRI has become a very useful tool in the diagnosis and follow-up of patients with
muscle dystrophies. Muscle MRI provides us about many aspects of the structure and …
muscle dystrophies. Muscle MRI provides us about many aspects of the structure and …