Bionanoparticles in cancer imaging, diagnosis, and treatment
Biological molecules such as DNA, proteins, and lipids can be assembled into naturally
existing nanoparticles, such as bacterial viruses (also called bacteriophages or phages) …
existing nanoparticles, such as bacterial viruses (also called bacteriophages or phages) …
[HTML][HTML] Engineered M13 phage as a novel therapeutic bionanomaterial for clinical applications: From tissue regeneration to cancer therapy
C Chang, W Guo, X Yu, C Guo, N Zhou, X Guo… - Materials Today Bio, 2023 - Elsevier
Bacteriophages (phages) are nanostructured viruses with highly selective antibacterial
properties that have gained attention beyond eliminating bacteria. Specifically, M13 phages …
properties that have gained attention beyond eliminating bacteria. Specifically, M13 phages …
[HTML][HTML] A comprehensive review on phage therapy and phage-based drug development
L Cui, S Watanabe, K Miyanaga, K Kiga, T Sasahara… - Antibiotics, 2024 - mdpi.com
Phage therapy, the use of bacteriophages (phages) to treat bacterial infections, is regaining
momentum as a promising weapon against the rising threat of multidrug-resistant (MDR) …
momentum as a promising weapon against the rising threat of multidrug-resistant (MDR) …
T7 phage as an emerging nanobiomaterial with genetically tunable target specificity
Bacteriophages, also known as phages, are specific antagonists against bacteria. T7 phage
has drawn massive attention in precision medicine owing to its distinctive advantages, such …
has drawn massive attention in precision medicine owing to its distinctive advantages, such …
Highly effective stroke therapy enabled by genetically engineered viral nanofibers
X Liu, M Yang, F Lei, Y Wang, M Yang… - Advanced …, 2022 - Wiley Online Library
Stroke results in the formation of a cavity in the infarcted brain tissue. Angiogenesis and
neurogenesis are poor in the cavity, preventing brain‐tissue regeneration for stroke therapy …
neurogenesis are poor in the cavity, preventing brain‐tissue regeneration for stroke therapy …
Harnessing virus flexibility to selectively capture and profile rare circulating target cells for precise cancer subty**
HD Li, YQ Chen, Y Li, X Wei, SY Wang, Y Cao… - Nature …, 2024 - nature.com
The effective isolation of rare target cells, such as circulating tumor cells, from whole blood is
still challenging due to the lack of a capturing surface with strong target-binding affinity and …
still challenging due to the lack of a capturing surface with strong target-binding affinity and …
Viruses as biomaterials
Viruses lacking the capacity to infect mammals exhibit minimal toxicity, good
biocompatibility, and well-defined structures. As self-organized biomolecular assemblies …
biocompatibility, and well-defined structures. As self-organized biomolecular assemblies …
Selectively suppressing tumor angiogenesis for targeted breast cancer therapy by genetically engineered phage
Antiangiogenesis is a promising approach to cancer therapy but is limited by the lack of
tumor‐homing capability of the current antiangiogenic agents. Angiogenin, a protein …
tumor‐homing capability of the current antiangiogenic agents. Angiogenin, a protein …
Stemness maintenance and massproduction of neural stem cells on poly L‐lactic acid nanofibrous membrane based on piezoelectriceffect
X Lu, C Sun, L Chen, Z Feng, H Gao, S Hu, M Dong… - Small, 2022 - Wiley Online Library
Neural stem cells (NSCs) therapy is promising for treating neurodegenerative disorders and
neural injuries. However, the limited in vitro expansion, spontaneous differentiation, and …
neural injuries. However, the limited in vitro expansion, spontaneous differentiation, and …
Integration of genetically engineered virus nanofibers and fibrin to form injectable fibrous neuron-rich hydrogels and enable neural differentiation
Peripheral nerve injury (PNI) results in persistent pain, a burning sensation, tingling, or
complete loss of sensation. Treating large nerve defects is a major challenge, and the use of …
complete loss of sensation. Treating large nerve defects is a major challenge, and the use of …