As global life expectancy increases, age-related brain diseases such as stroke and
dementia have become leading causes of death and disability. The aging of the …

Leptomeningeal collaterals (LMCs) are crucial in mitigating the impact of acute ischemic
stroke (AIS) by providing alternate blood flow routes when primary arteries are obstructed …

Understanding the morphology and function of large-scale cerebrovascular networks is
crucial for studying brain health and disease. However, reconciling the demands for imaging …

Futile reperfusion is a phenomenon of inadequate perfusion despite successful
recanalization after acute ischemic stroke (AIS). It is associated with poor patient outcomes …

Objective: This study aims to develop and validate the Futile Recanalization Prediction
Score (FRPS), a novel tool designed to predict the severity risk of FR and aid in pre-and post …

The pial vasculature is the sole source of blood supply to the neocortex. The brain is
contained within the skull, a vascularized bone marrow with a unique anatomical connection …

Ischemic stroke and vascular cognitive impairment, caused by a sudden arterial occlusion or
more subtle but protracted vascular insufficiency, respectively, are leading causes of …

Ischemic stroke research has enabled significant advancements in diagnosis, treatment, and
management of this debilitating disease, yet challenges remain standing in the way of better …

Neurovascular coupling (NVC) refers to the process of local changes in cerebral blood flow
(CBF) after neuronal activity, which ensures the timely and adequate supply of oxygen …

It has been estimated that approximately two million neurons, sixteen billion synapses and
twelve kilometers of axons are lost each minute following anterior large-vessel stroke. The …