Protein corona: a new approach for nanomedicine design
After administration of nanoparticle (NP) into biological fluids, an NP–protein complex is
formed, which represents the “true identity” of NP in our body. Hence, protein–NP interaction …
formed, which represents the “true identity” of NP in our body. Hence, protein–NP interaction …
The role of surface charge in cellular uptake and cytotoxicity of medical nanoparticles
E Fröhlich - International journal of nanomedicine, 2012 - Taylor & Francis
Many types of nanoparticles (NPs) are tested for use in medical products, particularly in
imaging and gene and drug delivery. For these applications, cellular uptake is usually a …
imaging and gene and drug delivery. For these applications, cellular uptake is usually a …
Understanding and controlling the interaction of nanomaterials with proteins in a physiological environment
Nanomaterials hold promise as multifunctional diagnostic and therapeutic agents. However,
the effective application of nanomaterials is hampered by limited understanding and control …
the effective application of nanomaterials is hampered by limited understanding and control …
The evolution of the protein corona around nanoparticles: a test study
The importance of the protein corona formed around nanoparticles upon entering a
biological fluid has recently been highlighted. This corona is, when sufficiently long-lived …
biological fluid has recently been highlighted. This corona is, when sufficiently long-lived …
Particle shape enhances specificity of antibody-displaying nanoparticles
Monoclonal antibodies are used in numerous therapeutic and diagnostic applications;
however, their efficacy is contingent on specificity and avidity. Here, we show that …
however, their efficacy is contingent on specificity and avidity. Here, we show that …
Preformed albumin corona, a protective coating for nanoparticles based drug delivery system
Q Peng, S Zhang, Q Yang, T Zhang, XQ Wei, L Jiang… - Biomaterials, 2013 - Elsevier
The non-specific interaction between nanoparticles (NPs) and plasma proteins occurs
immediately after NPs enter the blood, resulting in the formation of the protein corona that …
immediately after NPs enter the blood, resulting in the formation of the protein corona that …
Nanoparticle–blood interactions: the implications on solid tumour targeting
Nanoparticles are suitable platforms for cancer targeting and diagnostic applications.
Typically, less than 10% of all systemically administered nanoparticles accumulate in the …
Typically, less than 10% of all systemically administered nanoparticles accumulate in the …
Biosafety and bioapplication of nanomaterials by designing protein–nanoparticle interactions
ST Yang, Y Liu, YW Wang, A Cao - Small, 2013 - Wiley Online Library
The protein–nanoparticle (NP) interface is a current frontier of multiple disciplines, full of
challenges and opportunities. The unique behaviors of nanomaterials (NMs) bring many …
challenges and opportunities. The unique behaviors of nanomaterials (NMs) bring many …
[HTML][HTML] The uptake of PLGA micro or nanoparticles by macrophages provokes distinct in vitro inflammatory response
Biodegradable micro/nanoparticles generated from PLGA have recently attracted attention
due to their clinically proven biocompatibility, especially for immunization purposes. These …
due to their clinically proven biocompatibility, especially for immunization purposes. These …
Silver nanoparticle protein corona composition in cell culture media
The potential applications of nanomaterials as drug delivery systems and in other products
continue to expand. Upon introduction into physiological environments and driven by …
continue to expand. Upon introduction into physiological environments and driven by …