Recent Advances in Alkenyl sp2 C–H and C–F Bond Functionalizations: Scope, Mechanism, and Applications

MZ Lu, J Goh, M Maraswami, Z Jia, JS Tian… - Chemical …, 2022 - ACS Publications
Alkenes and their derivatives are featured widely in a variety of natural products,
pharmaceuticals, and advanced materials. Significant efforts have been made toward the …

Pyrrole: a resourceful small molecule in key medicinal hetero-aromatics

V Bhardwaj, D Gumber, V Abbot, S Dhiman, P Sharma - Rsc Advances, 2015 - pubs.rsc.org
Pyrrole is widely known as a biologically active scaffold which possesses a diverse nature of
activities. The combination of different pharmacophores in a pyrrole ring system has led to …

Recent advances in transition metal-free annulation toward heterocycle diversity based on the C–N bond cleavage of enaminone platform

XY Chen, X Zhang, JP Wan - Organic & Biomolecular Chemistry, 2022 - pubs.rsc.org
Enaminones and analogous stable enamines are well known as platform building blocks in
organic synthesis for the construction of heterocyclic compounds, especially N-heterocycles …

Formal [4+ 1] annulation reactions in the synthesis of carbocyclic and heterocyclic systems

JR Chen, XQ Hu, LQ Lu, WJ **ao - Chemical reviews, 2015 - ACS Publications
The development of new strategies and chemical reactions continues to be a major focus of
research efforts in the modern synthetic organic community. 1 Of the various types of …

An insight into the advanced synthetic recipes to access ubiquitous indole heterocycles

BS Mathada, NG Yernale, JN Basha, J Badiger - Tetrahedron Letters, 2021 - Elsevier
Indoles are amongst the most essential class of heteroaromatics in organic chemistry, being
commonly found in biologically active natural products. Indole and its derivatives have …

Rhodium‐Catalyzed C H Annulation of Nitrones with Alkynes: A Regiospecific Route to Unsymmetrical 2, 3‐Diaryl‐Substituted Indoles

H Yan, H Wang, X Li, X **n, C Wang… - Angewandte …, 2015 - Wiley Online Library
Abstract The direct C H annulation of anilines or related compounds with internal alkynes
provides straightforward access to 2, 3‐disubstituted indole products. However, this …

Regiocontrolled synthesis of polysubstituted pyrroles starting from terminal alkynes, sulfonyl azides, and allenes

T Miura, K Hiraga, T Biyajima, T Nakamuro… - Organic …, 2013 - ACS Publications
1-Sulfonyl-1, 2, 3-triazoles, readily prepared from terminal alkynes and sulfonyl azides, react
with allenes in the presence of a nickel (0) catalyst to produce the corresponding …

Recent developments in the synthesis of nitrogen-containing heterocycles from β-aminovinyl esters/ketones as C [double bond, length as m-dash] C–N donors

XF **a, YN Niu - Organic & Biomolecular Chemistry, 2022 - pubs.rsc.org
Nitrogen-containing heterocycles are ubiquitous fragments of numerous natural products,
pharmaceuticals, designed bioactive drug candidates and agrochemicals. During the past …

Synthesis of Pyrroles from Terminal Alkynes, N-Sulfonyl Azides, and Alkenyl Alkyl Ethers through 1-Sulfonyl-1,2,3-triazoles

CE Kim, S Park, D Eom, B Seo, PH Lee - Organic letters, 2014 - ACS Publications
A method for synthesis of substituted pyrroles has been developed. 1-Sulfonyl-1, 2, 3-
triazoles generated from terminal alkynes gave α-imino rhodium carbene complexes, which …

Synthesis of diverse pentasubstituted pyrroles by a gold (I)-catalyzed cascade rearrangement-cyclization of tertiary enamide

W Li, R Shi, S Chen, X Zhang, W Peng… - The Journal of …, 2022 - ACS Publications
An efficient Au (I)-catalyzed intramolecular cascade reaction of tertiary enamides tethered an
alkynyl group has been developed. The process is composed of a propargyl-claisen …