Turnitin
降AI改写
早检测系统
早降重系统
Turnitin-UK版
万方检测-期刊版
维普编辑部版
Grammarly检测
Paperpass检测
checkpass检测
PaperYY检测
The MYC oncogene — the grand orchestrator of cancer growth and immune evasion
The MYC proto-oncogenes encode a family of transcription factors that are among the most
commonly activated oncoproteins in human neoplasias. Indeed, MYC aberrations or …
commonly activated oncoproteins in human neoplasias. Indeed, MYC aberrations or …
Epidermal growth factor receptor mutations in lung cancer
The development and clinical application of inhibitors that target the epidermal growth factor
receptor (EGFR) provide important insights for new lung cancer therapies, as well as for the …
receptor (EGFR) provide important insights for new lung cancer therapies, as well as for the …
MYCN mediates TFRC-dependent ferroptosis and reveals vulnerabilities in neuroblastoma
Y Lu, Q Yang, Y Su, Y Ji, G Li, X Yang, L Xu, Z Lu… - Cell death & …, 2021 - nature.com
MYCN amplification is tightly associated with the poor prognosis of pediatric neuroblastoma
(NB). The regulation of NB cell death by MYCN represents an important aspect, as it directly …
(NB). The regulation of NB cell death by MYCN represents an important aspect, as it directly …
Reflecting on 25 years with MYC
Just over 25 years ago, MYC, the human homologue of a retroviral oncogene, was
identified. Since that time, MYC research has been intense and the advances impressive …
identified. Since that time, MYC research has been intense and the advances impressive …
MYC function and regulation in physiological perspective
MYC, a key member of the Myc-proto-oncogene family, is a universal transcription amplifier
that regulates almost every physiological process in a cell including cell cycle, proliferation …
that regulates almost every physiological process in a cell including cell cycle, proliferation …
Apoptosis. Its significance in cancer and cancer therapy
JFR Kerr, CM Winterford, BV Harmon - Cancer, 1994 - Wiley Online Library
Apoptosis is a distinct mode of cell death that is responsible for deletion of cells in normal
tissues; it also occurs in specific pathologic contexts. Morphologically, it involves rapid …
tissues; it also occurs in specific pathologic contexts. Morphologically, it involves rapid …
Cell cycle control and cancer
LH Hartwell, MB Kastan - Science, 1994 - science.org
Multiple genetic changes occur during the evolution of normal cells into cancer cells. This
evolution is facilitated in cancer cells by loss of fidelity in the processes that replicate, repair …
evolution is facilitated in cancer cells by loss of fidelity in the processes that replicate, repair …
Prediction of bone density from vitamin D receptor alleles
BONE density achieved in early adulthood is the major determinant of risk of osteoporotic
fracture. Up to 60% of women1, 2 suffer osteoporotic fractures as a result of low bone …
fracture. Up to 60% of women1, 2 suffer osteoporotic fractures as a result of low bone …
Oxidative stress as a mediator of apoptosis
Many agents which induce apoptosis are either oxidants or stimulators of cellular oxidative
metabolism. Conversely, many inhibitvrs of apoptosis have antioxidant activities or enhance …
metabolism. Conversely, many inhibitvrs of apoptosis have antioxidant activities or enhance …
Pathways of apoptotic and non-apoptotic death in tumour cells
H Okada, TW Mak - Nature Reviews Cancer, 2004 - nature.com
Defects in cell-death pathways are hallmarks of cancer. Although resistance to apoptosis is
closely linked to tumorigenesis, tumour cells can still be induced to die by non-apoptotic …
closely linked to tumorigenesis, tumour cells can still be induced to die by non-apoptotic …