Designer self‐assembling peptide hydrogels to engineer 3D cell microenvironments for cell constructs formation and precise oncology remodeling in ovarian cancer

Z Yang, H Xu, X Zhao - Advanced Science, 2020 - Wiley Online Library
Designer self‐assembling peptides form the entangled nanofiber networks in hydrogels by
ionic‐complementary self‐assembly. This type of hydrogel has realistic biological and …

Updates of pathogenesis, diagnostic and therapeutic perspectives for ovarian clear cell carcinoma

C Zhu, Z Xu, T Zhang, L Qian, W **ao, H Wei… - Journal of …, 2021 - pmc.ncbi.nlm.nih.gov
Ovarian clear cell carcinoma (OCCC) is a special pathological type of epithelial ovarian
carcinoma (EOC) and has a high prevalence in Asia without specific molecular subtype …

Cyclin B2 overexpression in human hepatocellular carcinoma is associated with poor prognosis

R Li, X Jiang, Y Zhang, S Wang, X Chen, X Yu… - Archives of medical …, 2019 - Elsevier
Background and aims Cyclin B2 (CCNB2) has been reported to be highly expressed in a
few malignancies. However, the biological function of CCNB2 in hepatocellular carcinoma …

FRMD8 targets both CDK4 activation and RB degradation to suppress colon cancer growth

M Yu, W Wu, Y Sun, H Yan, L Zhang, Z Wang, Y Gong… - Cell Reports, 2023 - cell.com
Summary Cyclin-dependent kinase 4 (CDK4) and retinoblastoma protein (RB) are both
important cell-cycle regulators that function in different scenarios. Here, we report that FERM …

A comprehensive molecular analysis of 113 primary ovarian clear cell carcinomas reveals common therapeutically significant aberrations

I Stružinská, N Hájková, J Hojný, E Krkavcová… - Diagnostic …, 2023 - Springer
Background Molecular aberrations occurring in primary ovarian clear cell carcinoma
(OCCC) can be of diagnostic, predictive, and prognostic significance. However, a complex …

Identification of lncRNAs deregulated in epithelial ovarian cancer based on a gene expression profiling meta-analysis

M Salamini-Montemurri, M Lamas-Maceiras… - International Journal of …, 2023 - mdpi.com
Epithelial ovarian cancer (EOC) is one of the deadliest gynecological cancers worldwide,
mainly because of its initially asymptomatic nature and consequently late diagnosis. Long …

Transcriptomic analyses of ovarian clear-cell carcinoma with concurrent endometriosis

KE Collins, X Wang, Y Klymenko, NB Davis… - Frontiers in …, 2023 - frontiersin.org
Introduction Endometriosis, a benign inflammatory disease whereby endometrial-like tissue
grows outside the uterus, is a risk factor for endometriosis-associated ovarian cancers. In …

Endometrioid ovarian carcinoma landscape: pathological and molecular characterization

A de Nonneville, E Kalbacher, F Cannone… - Molecular …, 2024 - Wiley Online Library
Endometrioid ovarian cancers (EOvC) are usually managed as serous tumors. In this study,
we conducted a comprehensive molecular investigation to uncover the distinct biological …

[HTML][HTML] Systematic identification of characteristic genes of ovarian clear cell carcinoma compared with high-grade serous carcinoma based on RNA-sequencing

S Nagasawa, K Ikeda, K Horie-Inoue, S Sato… - International journal of …, 2019 - mdpi.com
Objective: Ovarian cancer has the highest mortality among gynecological cancers. High-
grade serous carcinoma (HGSC) is the most common histotype of ovarian cancer regardless …

Integrative genomics approach identifies molecular features associated with early-stage ovarian carcinoma histotypes

H Engqvist, TZ Parris, J Biermann, EW Rönnerman… - Scientific reports, 2020 - nature.com
Ovarian cancer comprises multiple subtypes (clear-cell (CCC), endometrioid (EC), high-
grade serous (HGSC), low-grade serous (LGSC), and mucinous carcinomas (MC)) with …