Endogenous photosensitizers in human skin
Endogenous photosensitizers play a critical role in both beneficial and harmful light-induced
transformations in biological systems. Understanding their mode of action is essential for …
transformations in biological systems. Understanding their mode of action is essential for …
Melanogenesis and the targeted therapy of melanoma
C Li, L Kuai, R Cui, X Miao - Biomolecules, 2022 - mdpi.com
Pigment production is a unique character of melanocytes. Numerous factors are linked with
melanin production, including genetics, ultraviolet radiation (UVR) and inflammation …
melanin production, including genetics, ultraviolet radiation (UVR) and inflammation …
Chemical and biochemical control of skin pigmentation with special emphasis on mixed melanogenesis
Melanins are widely distributed in animals and plants; in vertebrates, most melanins are
present on the body surface. The diversity of pigmentation in vertebrates is mainly attributed …
present on the body surface. The diversity of pigmentation in vertebrates is mainly attributed …
Disentangling the Puzzling Regiochemistry of Thiol Addition to o-Quinones
ML Alfieri, A Cariola, L Panzella… - The Journal of …, 2022 - ACS Publications
The addition of thiol compounds to o-quinones, as exemplified by the biologically relevant
conjugation of cysteine to dopaquinone, displays an anomalous 1, 6-type regiochemistry …
conjugation of cysteine to dopaquinone, displays an anomalous 1, 6-type regiochemistry …
Cuticular sclerotization in insects–A critical review
M Sugumaran - Advances in Insect Physiology, 2022 - Elsevier
Sclerotization of cuticle is a vital process for the survival of insects. It is caused by covalent
crosslinking of structural proteins and chitin to form hard and often coloured cuticle. During …
crosslinking of structural proteins and chitin to form hard and often coloured cuticle. During …
Identification of alkaline-induced thiolyl-chlorogenic acid conjugates with cysteine and glutathione
CT Drucker, AR Cicali, AMP Roberts, CA Hughey… - Food Chemistry, 2023 - Elsevier
Alkaline reactions of chlorogenic acid (CGA) yield undesirable development of brown or
green pigments, limiting the utilization of alkalized CGA-rich foods. Thiols such as cysteine …
green pigments, limiting the utilization of alkalized CGA-rich foods. Thiols such as cysteine …
A novel multi-target strategy to attenuate the progression of Parkinson's disease by diamine hybrid AGE/ALE inhibitor
NA Sasaki, P Sonnet - Future Medicinal Chemistry, 2021 - Taylor & Francis
Instead of a conventional 'one-drug-one-target approach', this article presents a novel multi-
target approach with a concept of trap** simultaneously as many detrimental factors as …
target approach with a concept of trap** simultaneously as many detrimental factors as …
Imidazo [1, 2-a] Pyridine Derivatives–Copper (II) Salts: Highly Effective In Situ Combination for Catecholase
In this work, we were interested in the search for new catalysts for catecholase, whose
principle is based on the oxidation reaction of catechol to o-quinone. In this context, a series …
principle is based on the oxidation reaction of catechol to o-quinone. In this context, a series …
Advances of curcumin in nervous system diseases: the effect of regulating oxidative stress and clinical studies
Y Wei, H Li, Y Li, Y Zeng, T Quan, Y Leng… - Frontiers in …, 2024 - frontiersin.org
In recent years, researchers have highly observed that neurological disorders (NSDs) with
the aging of the population are a global health burden whose prevalence is increasing every …
the aging of the population are a global health burden whose prevalence is increasing every …
[BOOK][B] Melanin chemistry explored by quantum mechanics
Melanin is important as a bearer of skin and hair color, that is, visual phenotype. Even within
the same species, the expressions of body color observed between individuals are diverse …
the same species, the expressions of body color observed between individuals are diverse …