Endogenous photosensitizers in human skin

EL Bastos, FH Quina, MS Baptista - Chemical Reviews, 2023 - ACS Publications
Endogenous photosensitizers play a critical role in both beneficial and harmful light-induced
transformations in biological systems. Understanding their mode of action is essential for …

Melanogenesis and the targeted therapy of melanoma

C Li, L Kuai, R Cui, X Miao - Biomolecules, 2022 - mdpi.com
Pigment production is a unique character of melanocytes. Numerous factors are linked with
melanin production, including genetics, ultraviolet radiation (UVR) and inflammation …

Chemical and biochemical control of skin pigmentation with special emphasis on mixed melanogenesis

K Wakamatsu, JH Zippin, S Ito - Pigment cell & melanoma …, 2021 - Wiley Online Library
Melanins are widely distributed in animals and plants; in vertebrates, most melanins are
present on the body surface. The diversity of pigmentation in vertebrates is mainly attributed …

Disentangling the Puzzling Regiochemistry of Thiol Addition to o-Quinones

ML Alfieri, A Cariola, L Panzella… - The Journal of …, 2022 - ACS Publications
The addition of thiol compounds to o-quinones, as exemplified by the biologically relevant
conjugation of cysteine to dopaquinone, displays an anomalous 1, 6-type regiochemistry …

Cuticular sclerotization in insects–A critical review

M Sugumaran - Advances in Insect Physiology, 2022 - Elsevier
Sclerotization of cuticle is a vital process for the survival of insects. It is caused by covalent
crosslinking of structural proteins and chitin to form hard and often coloured cuticle. During …

Identification of alkaline-induced thiolyl-chlorogenic acid conjugates with cysteine and glutathione

CT Drucker, AR Cicali, AMP Roberts, CA Hughey… - Food Chemistry, 2023 - Elsevier
Alkaline reactions of chlorogenic acid (CGA) yield undesirable development of brown or
green pigments, limiting the utilization of alkalized CGA-rich foods. Thiols such as cysteine …

A novel multi-target strategy to attenuate the progression of Parkinson's disease by diamine hybrid AGE/ALE inhibitor

NA Sasaki, P Sonnet - Future Medicinal Chemistry, 2021 - Taylor & Francis
Instead of a conventional 'one-drug-one-target approach', this article presents a novel multi-
target approach with a concept of trap** simultaneously as many detrimental factors as …

Imidazo [1, 2-a] Pyridine Derivatives–Copper (II) Salts: Highly Effective In Situ Combination for Catecholase

M Moutaouakil, C Abdelmjid, O Roby, S Tighadouini… - Chemistry Africa, 2023 - Springer
In this work, we were interested in the search for new catalysts for catecholase, whose
principle is based on the oxidation reaction of catechol to o-quinone. In this context, a series …

Advances of curcumin in nervous system diseases: the effect of regulating oxidative stress and clinical studies

Y Wei, H Li, Y Li, Y Zeng, T Quan, Y Leng… - Frontiers in …, 2024 - frontiersin.org
In recent years, researchers have highly observed that neurological disorders (NSDs) with
the aging of the population are a global health burden whose prevalence is increasing every …

[BOOK][B] Melanin chemistry explored by quantum mechanics

R Kishida, SM Aspera, H Kasai - 2021 - Springer
Melanin is important as a bearer of skin and hair color, that is, visual phenotype. Even within
the same species, the expressions of body color observed between individuals are diverse …