[HTML][HTML] Serious games in the new era of digital-health interventions: a narrative review of their therapeutic applications to manage neurobehavior in …

RA Vacca, A Augello, L Gallo, G Caggianese… - Neuroscience & …, 2023 - Elsevier
Children and adolescents with neurodevelopmental disorders generally show adaptive,
cognitive and motor skills impairments associated with behavioral problems, ie, alterations …

Mechanisms underlying the effect of voluntary running on adult hippocampal neurogenesis

Y Gao, M Syed, X Zhao - Hippocampus, 2023 - Wiley Online Library
Adult hippocampal neurogenesis is important for preserving learning and memory‐related
cognitive functions. Physical exercise, especially voluntary running, is one of the strongest …

Gut microbiota from persons with attention-deficit/hyperactivity disorder affects the brain in mice

AC Tengeler, SA Dam, M Wiesmann, J Naaijen… - Microbiome, 2020 - Springer
Background The impact of the gut microbiota on host physiology and behavior has been
relatively well established. Whether changes in microbial composition affect brain structure …

Early or late gestational exposure to maternal immune activation alters neurodevelopmental trajectories in mice: an integrated neuroimaging, behavioral, and …

E Guma, P do Couto Bordignon, GA Devenyi… - Biological …, 2021 - Elsevier
Background Exposure to maternal immune activation (MIA) in utero is a risk factor for
neurodevelopmental disorders later in life. The impact of the gestational timing of MIA …

Oxidative stress-induced damage to the develo** hippocampus is mediated by GSK3β

J Abbah, CM Vacher, EZ Goldstein, Z Li… - Journal of …, 2022 - jneurosci.org
Neonatal brain injury renders the develo** brain vulnerable to oxidative stress, leading to
cognitive deficit. However, oxidative stress-induced damage to hippocampal circuits and the …

Altered hippocampal neurogenesis in a mouse model of autism revealed by genetic polymorphisms and by atypical development of newborn neurons

I Barón-Mendoza, M Mejía-Hernández… - Scientific Reports, 2024 - nature.com
Individuals with autism spectrum disorder (ASD) often exhibit atypical hippocampal anatomy
and connectivity throughout their lifespan, potentially linked to alterations in the neurogenic …

Linking haploinsufficiency of the autism- and schizophrenia-associated gene Cyfip1 with striatal-limbic-cortical network dysfunction and cognitive inflexibility

JE Haddon, D Titherage, JR Heckenast, J Carter… - Translational …, 2024 - nature.com
Impaired behavioural flexibility is a core feature of neuropsychiatric disorders and is
associated with underlying dysfunction of fronto-striatal circuitry. Reduced dosage of Cyfip1 …

From synapses to circuits: What mouse models have taught us about how autism spectrum disorder impacts hippocampal function

L Severino, J Kim, MH Nam, TJ McHugh - Neuroscience & Biobehavioral …, 2024 - Elsevier
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder that impacts a
variety of cognitive and behavioral domains. While a genetic component of ASD has been …

MicroRNA-218 instructs proper assembly of hippocampal networks

SR Taylor, M Kobayashi, A Vilella, D Tiwari, N Zolboot… - Elife, 2023 - elifesciences.org
The assembly of the mammalian brain is orchestrated by temporally coordinated waves of
gene expression. Post-transcriptional regulation by microRNAs (miRNAs) is a key aspect of …

[HTML][HTML] Possible mechanisms of the neuroprotective actions of date palm fruits aqueous extracts against valproic acid-induced autism in rats

AM Hussein, SA Mahmoud, KM Elazab… - Current Issues in …, 2023 - mdpi.com
The current study aimed to determine how palm date aqueous fruit extracts (AFE) affected
the autistic-like behaviors brought on by valproic acid (VPA) injection, as well as any …