Biological foundations of successful bacteriophage therapy
Bacteriophages (phages) are selective viral predators of bacteria. Abundant and ubiquitous
in nature, phages can be used to treat bacterial infections (phage therapy), including …
in nature, phages can be used to treat bacterial infections (phage therapy), including …
Understanding the complex phage-host interactions in biofilm communities
Bacteriophages and bacterial biofilms are widely present in natural environments, a fact that
has accelerated the evolution of phages and their bacterial hosts in these particular niches …
has accelerated the evolution of phages and their bacterial hosts in these particular niches …
Phage Paride can kill dormant, antibiotic-tolerant cells of Pseudomonas aeruginosa by direct lytic replication
Bacteriophages are ubiquitous viral predators that have primarily been studied using fast-
growing laboratory cultures of their bacterial hosts. However, microbial life in nature is …
growing laboratory cultures of their bacterial hosts. However, microbial life in nature is …
Combination of genetically diverse Pseudomonas phages enhances the cocktail efficiency against bacteria
Phage treatment has been used as an alternative to antibiotics since the early 1900s.
However, bacteria may acquire phage resistance quickly, limiting the use of phage …
However, bacteria may acquire phage resistance quickly, limiting the use of phage …
[HTML][HTML] A comprehensive review on phage therapy and phage-based drug development
Phage therapy, the use of bacteriophages (phages) to treat bacterial infections, is regaining
momentum as a promising weapon against the rising threat of multidrug-resistant (MDR) …
momentum as a promising weapon against the rising threat of multidrug-resistant (MDR) …
Unveil the secret of the bacteria and phage arms race
Bacteria have developed different mechanisms to defend against phages, such as
preventing phages from being adsorbed on the surface of host bacteria; through the …
preventing phages from being adsorbed on the surface of host bacteria; through the …
Genome-driven elucidation of phage-host interplay and impact of phage resistance evolution on bacterial fitness
When considering the interactions between bacteriophages and their host, the issue of
phage-resistance emergence is a key element in understanding the ecological impact of …
phage-resistance emergence is a key element in understanding the ecological impact of …
[HTML][HTML] An overview of the current state of phage therapy for the treatment of biofilm-related infections
Bacterial biofilms are involved in many chronic and difficult-to-treat infections. Phage therapy
against infectious biofilms is becoming a promising strategy, as suggested by the increasing …
against infectious biofilms is becoming a promising strategy, as suggested by the increasing …
A novel method to create efficient phage cocktails via use of phage-resistant bacteria
The rapid antiphage mutation of pathogens is a big challenge often encountered in the
application of phages in aquaculture, animal husbandry, and human disease prevention. A …
application of phages in aquaculture, animal husbandry, and human disease prevention. A …
Profiles of phage in global hospital wastewater: Association with microbial hosts, antibiotic resistance genes, metal resistance genes, and mobile genetic elements
Y Kang, J Wang, Y Wang, Z Li - Science of The Total Environment, 2024 - Elsevier
Hospital wastewater (HWW) is known to host taxonomically diverse microbial communities,
yet limited information is available on the phages infecting these microorganisms. To fill this …
yet limited information is available on the phages infecting these microorganisms. To fill this …