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[HTML][HTML] Therapeutic outcomes of isatin and its derivatives against multiple diseases: recent developments in drug discovery
Isatin (1 H indole 2, 3-dione) is a heterocyclic, endogenous lead molecule recognized in
humans and different plants. The isatin nucleus and its derivatives are owed the attention of …
humans and different plants. The isatin nucleus and its derivatives are owed the attention of …
Isatin derivatives with potential antitubercular activities
D Jiang, GQ Wang, X Liu, Z Zhang… - Journal of …, 2018 - Wiley Online Library
Tuberculosis is a life‐threatening chronic infectious disease, which primarily affects the
lungs but can spread to other vital organs. The re‐emergence and wide spread of new …
lungs but can spread to other vital organs. The re‐emergence and wide spread of new …
Unlocking the biological potential of transition metal complexes with Thiosemicarbazone ligands: Insights from computational studies
In the previous study, the synthesis and characterization of 4-(3-fluorophenyl)-3-
thiosemicarbazide and benzaldehyde derivatives based thiosemicarbazone ligands and …
thiosemicarbazide and benzaldehyde derivatives based thiosemicarbazone ligands and …
Novel isatin–triazole based thiosemicarbazones as potential anticancer agents: synthesis, DFT and molecular docking studies
Thiosemicarbazones of isatin have been found to exhibit versatile bioactivities. In this study,
two distinct types of isatin–triazole hybrids 3a and 3b were accessed via copper-catalyzed …
two distinct types of isatin–triazole hybrids 3a and 3b were accessed via copper-catalyzed …
Design and synthesis of heterocyclic azole based bioactive compounds: Molecular structures, quantum simulation, and mechanistic studies through docking as multi …
Abstract Two heterocyclic azole compounds, 3-(2, 3-dihydrobenzo [d] thiazol-2-yl)-4H-
chromen-4-one (SVS1) and 5-(1H-indol-3-yl)-4-methyl-2, 4-dihydro-3H-1, 2, 4-triazole-3 …
chromen-4-one (SVS1) and 5-(1H-indol-3-yl)-4-methyl-2, 4-dihydro-3H-1, 2, 4-triazole-3 …
Synthesis, structural elucidation, DFT investigations, biological evaluation and molecular docking studies of tetraamide-based macrocyclic cobalt (II) complexes
A new series of 16–18 membered cobalt (II) macrocyclic complexes derived by 3, 4-
diaminobenzophenone have been synthesized. The elemental analysis, FT-IR, 1H NMR …
diaminobenzophenone have been synthesized. The elemental analysis, FT-IR, 1H NMR …
Synthesis, structural characterization, thermal analysis, DFT, biocidal evaluation and molecular docking studies of amide-based Co (II) complexes
Many distinct amino acid and aromatic amine-derived transition metal complexes are used
as physiologically active compounds. A few Cobalt (II) complexes have been synthesized by …
as physiologically active compounds. A few Cobalt (II) complexes have been synthesized by …
Nickel (II) bis (isatin thiosemicarbazone) complexes induced apoptosis through mitochondrial signaling pathway and G0/G1 cell cycle arrest in IM-9 cells
Abstract Three novel complexes (1, 3 and 4) ligating N-substituted isatin thiosemicarbazone
derivatives have been synthesized and their structural and biological characteristics have …
derivatives have been synthesized and their structural and biological characteristics have …
Synthesis of Ni (II) complexes bearing indole-based thiosemicarbazone ligands for interaction with biomolecules and some biological applications
A series of new Ni (II) complexes containing indole-based thiosemicarbazone ligands was
synthesized and characterized by elemental analyses, and UV–visible, FT-IR, 1 H & 13 C …
synthesized and characterized by elemental analyses, and UV–visible, FT-IR, 1 H & 13 C …
Copper, nickel and zinc complexes of 3-acetyl coumarin thiosemicarbazone: Synthesis, characterization and in vitro evaluation of cytotoxicity and DNA/protein binding …
A new 3-acetylcoumarin thiosemicarbazone (AcTsc) and its copper (II)(1), nickel (II)(2) and
zinc (II)(3) complexes were synthesized and characterized by elemental analysis, UV–Vis …
zinc (II)(3) complexes were synthesized and characterized by elemental analysis, UV–Vis …